MLEC | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	21 studies	26% ± 10%	Explore
fibroblast	21 studies	27% ± 10%	Explore
macrophage	17 studies	24% ± 9%	Explore
plasmacytoid dendritic cell	15 studies	35% ± 8%	Explore
smooth muscle cell	14 studies	23% ± 7%	Explore
conventional dendritic cell	13 studies	26% ± 12%	Explore
ciliated cell	13 studies	37% ± 11%	Explore
natural killer cell	12 studies	20% ± 5%	Explore
pericyte	12 studies	26% ± 8%	Explore
plasma cell	11 studies	40% ± 14%	Explore
epithelial cell	11 studies	50% ± 19%	Explore
plasmablast	9 studies	53% ± 23%	Explore
basal cell	9 studies	29% ± 14%	Explore
connective tissue cell	9 studies	30% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	18% ± 4%	Explore
myofibroblast cell	8 studies	26% ± 8%	Explore
abnormal cell	8 studies	31% ± 7%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 2%	Explore
progenitor cell	7 studies	42% ± 14%	Explore
type II pneumocyte	6 studies	29% ± 17%	Explore
hematopoietic precursor cell	6 studies	34% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	19% ± 4%	Explore
intestinal crypt stem cell	6 studies	45% ± 16%	Explore
mesothelial cell	6 studies	35% ± 15%	Explore
transit amplifying cell	6 studies	48% ± 26%	Explore
myeloid cell	6 studies	26% ± 11%	Explore
capillary endothelial cell	6 studies	25% ± 7%	Explore
oligodendrocyte precursor cell	6 studies	28% ± 8%	Explore
type I pneumocyte	5 studies	27% ± 9%	Explore
secretory cell	5 studies	34% ± 13%	Explore
classical monocyte	5 studies	24% ± 9%	Explore
mature NK T cell	5 studies	17% ± 1%	Explore
goblet cell	5 studies	34% ± 7%	Explore
IgA plasma cell	5 studies	22% ± 7%	Explore
dendritic cell	5 studies	37% ± 20%	Explore
astrocyte	5 studies	24% ± 6%	Explore
neuron	5 studies	27% ± 10%	Explore
gamma-delta T cell	5 studies	24% ± 18%	Explore
mast cell	5 studies	25% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 1%	Explore
T cell	4 studies	20% ± 5%	Explore
club cell	4 studies	30% ± 6%	Explore
leukocyte	4 studies	24% ± 8%	Explore
CD4-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
epithelial cell of proximal tubule	4 studies	24% ± 7%	Explore
renal alpha-intercalated cell	4 studies	25% ± 6%	Explore
enterocyte	4 studies	25% ± 5%	Explore
enteroendocrine cell	4 studies	30% ± 8%	Explore
IgG plasma cell	4 studies	26% ± 7%	Explore
monocyte	4 studies	27% ± 2%	Explore
microglial cell	4 studies	24% ± 4%	Explore
innate lymphoid cell	4 studies	18% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	31% ± 9%	Explore
regulatory T cell	4 studies	18% ± 2%	Explore
ionocyte	3 studies	26% ± 3%	Explore
respiratory goblet cell	3 studies	37% ± 11%	Explore
pancreatic A cell	3 studies	34% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	26% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
mononuclear phagocyte	3 studies	33% ± 18%	Explore
non-classical monocyte	3 studies	27% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	32% ± 13%	Explore
neural crest cell	3 studies	24% ± 2%	Explore
kidney loop of Henle epithelial cell	3 studies	28% ± 9%	Explore
extravillous trophoblast	3 studies	30% ± 11%	Explore
common myeloid progenitor	3 studies	33% ± 9%	Explore
endothelial cell of vascular tree	3 studies	18% ± 2%	Explore
GABAergic neuron	3 studies	37% ± 9%	Explore
glutamatergic neuron	3 studies	42% ± 12%	Explore
pancreatic ductal cell	3 studies	42% ± 23%	Explore
granulocyte monocyte progenitor cell	3 studies	45% ± 11%	Explore
megakaryocyte	3 studies	42% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 10%	Explore
interneuron	3 studies	30% ± 16%	Explore
oligodendrocyte	3 studies	21% ± 1%	Explore
erythroblast	3 studies	27% ± 8%	Explore
hepatocyte	3 studies	41% ± 21%	Explore
luminal cell of prostate epithelium	3 studies	25% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
intestine	9 studies	28% ± 11%	Explore
lung	8 studies	31% ± 11%	Explore
brain	6 studies	30% ± 7%	Explore
kidney	5 studies	20% ± 3%	Explore
peripheral blood	4 studies	23% ± 7%	Explore
liver	4 studies	28% ± 11%	Explore
pancreas	3 studies	42% ± 10%	Explore
uterus	3 studies	31% ± 19%	Explore
breast	3 studies	20% ± 3%	Explore
bone marrow	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	10973.64	966 / 966	100%	243.26	527 / 527
prostate	100%	10799.43	245 / 245	100%	197.75	502 / 502
stomach	100%	7867.75	359 / 359	100%	199.85	286 / 286
breast	100%	7046.62	459 / 459	100%	136.75	1117 / 1118
kidney	100%	9462.73	89 / 89	100%	193.06	899 / 901
thymus	100%	14319.61	653 / 653	100%	130.81	602 / 605
esophagus	100%	5147.16	1443 / 1445	99%	123.50	182 / 183
pancreas	100%	9230.05	328 / 328	99%	86.05	176 / 178
skin	99%	6839.75	1791 / 1809	100%	175.16	471 / 472
liver	100%	11532.70	226 / 226	99%	94.52	401 / 406
adrenal gland	100%	24560.84	258 / 258	99%	131.01	227 / 230
brain	99%	5108.73	2622 / 2642	99%	95.36	701 / 705
lung	99%	6086.77	573 / 578	99%	110.05	1149 / 1155
bladder	100%	7046.48	21 / 21	99%	123.67	497 / 504
ovary	100%	8033.73	180 / 180	99%	94.43	424 / 430
uterus	100%	7451.25	170 / 170	98%	91.52	450 / 459
adipose	100%	7597.17	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	149.67	80 / 80
lymph node	0%	0	0 / 0	100%	68.98	29 / 29
spleen	100%	7663.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	74.16	45 / 45
ureter	0%	0	0 / 0	100%	47.97	1 / 1
blood vessel	100%	5786.16	1330 / 1335	0%	0	0 / 0
muscle	100%	5741.54	799 / 803	0%	0	0 / 0
heart	99%	10126.92	856 / 861	0%	0	0 / 0
peripheral blood	61%	4473.71	571 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006487	Biological process	protein N-linked glycosylation
GO_0008250	Cellular component	oligosaccharyltransferase complex
GO_0005783	Cellular component	endoplasmic reticulum
GO_0035579	Cellular component	specific granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0019899	Molecular function	enzyme binding
GO_0030246	Molecular function	carbohydrate binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MLEC
Protein name	Malectin
Synonyms	KIAA0152
Description	FUNCTION: Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity). .
Accessions	ENST00000228506.8 Q14165 ENST00000412616.2 F5H1S8 ENST00000545525.5 ENST00000535656.1 H0YG07 F5GX14

MLEC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review