RPL13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006412Biological processtranslation
GO_0001824Biological processblastocyst development
GO_0060348Biological processbone development
GO_0002181Biological processcytoplasmic translation
GO_0005730Cellular componentnucleolus
GO_0022626Cellular componentcytosolic ribosome
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0016020Cellular componentmembrane
GO_0022625Cellular componentcytosolic large ribosomal subunit
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003735Molecular functionstructural constituent of ribosome
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameRPL13
Protein nameRibosomal protein L13
Large ribosomal subunit protein eL13 (60S ribosomal protein L13) (Breast basic conserved protein 1)
60S ribosomal protein L13
SynonymsOK/SW-cl.46
BBC1
hCG_1723872
DescriptionFUNCTION: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs . Plays a role in bone development . .

AccessionsA8K4C8
Q6NZ55
ENST00000472354.1
H3BTH3
ENST00000311528.10 [P26373-1]
P26373
ENST00000567815.5 [P26373-1]
ENST00000467736.5
ENST00000563270.5
ENST00000452368.7 [P26373-2]
ENST00000393099.3 [P26373-1]
J3QSB4
H3BUK8
ENST00000562879.5
J3KS98