Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 14 studies | 26% ± 8% | |
| oligodendrocyte | 9 studies | 28% ± 9% | |
| glutamatergic neuron | 8 studies | 36% ± 23% | |
| pericyte | 8 studies | 21% ± 4% | |
| smooth muscle cell | 7 studies | 23% ± 5% | |
| macrophage | 7 studies | 21% ± 5% | |
| GABAergic neuron | 7 studies | 39% ± 21% | |
| astrocyte | 7 studies | 30% ± 13% | |
| B cell | 6 studies | 21% ± 5% | |
| neuron | 5 studies | 38% ± 14% | |
| retinal ganglion cell | 5 studies | 62% ± 26% | |
| epithelial cell | 5 studies | 27% ± 7% | |
| oligodendrocyte precursor cell | 5 studies | 31% ± 10% | |
| natural killer cell | 4 studies | 19% ± 3% | |
| microglial cell | 4 studies | 24% ± 6% | |
| myeloid cell | 4 studies | 23% ± 6% | |
| cardiac muscle cell | 4 studies | 19% ± 3% | |
| basal cell | 4 studies | 19% ± 4% | |
| fibroblast | 4 studies | 20% ± 2% | |
| gamma-delta T cell | 4 studies | 18% ± 5% | |
| interneuron | 4 studies | 47% ± 24% | |
| classical monocyte | 3 studies | 23% ± 6% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 22% ± 6% | |
| non-classical monocyte | 3 studies | 27% ± 6% | |
| GABAergic interneuron | 3 studies | 21% ± 4% | |
| granule cell | 3 studies | 19% ± 2% | |
| ciliated cell | 3 studies | 22% ± 2% | |
| lymphocyte | 3 studies | 19% ± 4% | |
| endothelial cell of vascular tree | 3 studies | 22% ± 8% | |
| type I pneumocyte | 3 studies | 21% ± 6% | |
| CD8-positive, alpha-beta T cell | 3 studies | 19% ± 5% | |
| endothelial cell of lymphatic vessel | 3 studies | 22% ± 6% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 19% ± 3% | |
| plasmacytoid dendritic cell | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 9339.53 | 2642 / 2642 | 100% | 65.03 | 705 / 705 |
| kidney | 100% | 3888.55 | 89 / 89 | 100% | 31.31 | 901 / 901 |
| prostate | 100% | 4531.27 | 245 / 245 | 100% | 21.50 | 501 / 502 |
| breast | 100% | 4726.73 | 459 / 459 | 100% | 27.40 | 1114 / 1118 |
| lung | 100% | 5475.35 | 578 / 578 | 100% | 19.66 | 1150 / 1155 |
| thymus | 100% | 4561.49 | 652 / 653 | 100% | 23.68 | 602 / 605 |
| skin | 99% | 2884.13 | 1797 / 1809 | 100% | 37.01 | 472 / 472 |
| bladder | 100% | 4952.43 | 21 / 21 | 99% | 17.65 | 499 / 504 |
| stomach | 100% | 3935.87 | 359 / 359 | 99% | 16.63 | 283 / 286 |
| intestine | 100% | 5338.34 | 966 / 966 | 99% | 16.02 | 521 / 527 |
| uterus | 100% | 5297.11 | 170 / 170 | 98% | 16.18 | 452 / 459 |
| esophagus | 99% | 5965.33 | 1437 / 1445 | 99% | 15.25 | 181 / 183 |
| adrenal gland | 100% | 4156.95 | 258 / 258 | 98% | 66.76 | 225 / 230 |
| ovary | 100% | 3975.23 | 180 / 180 | 97% | 12.01 | 419 / 430 |
| liver | 97% | 2080.78 | 219 / 226 | 97% | 13.90 | 395 / 406 |
| pancreas | 87% | 1611.70 | 285 / 328 | 98% | 18.77 | 175 / 178 |
| adipose | 100% | 5033.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 9678.09 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 53.54 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.77 | 29 / 29 |
| spleen | 100% | 4292.65 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.71 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.44 | 1 / 1 |
| heart | 98% | 5351.45 | 846 / 861 | 0% | 0 | 0 / 0 |
| muscle | 96% | 2011.15 | 773 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 5104.94 | 888 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0140042 | Biological process | lipid droplet formation |
| GO_0006655 | Biological process | phosphatidylglycerol biosynthetic process |
| GO_0016024 | Biological process | CDP-diacylglycerol biosynthetic process |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0004605 | Molecular function | phosphatidate cytidylyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CDS2 |
| Protein name | Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol . Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid . Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis . . |
| Accessions | ENST00000450570.1 [O95674-2] O95674 ENST00000460006.6 [O95674-1] |