CNBP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	41 studies	54% ± 20%	Explore
natural killer cell	40 studies	49% ± 16%	Explore
B cell	39 studies	53% ± 14%	Explore
endothelial cell	39 studies	47% ± 19%	Explore
macrophage	36 studies	43% ± 15%	Explore
CD8-positive, alpha-beta T cell	35 studies	56% ± 18%	Explore
T cell	34 studies	49% ± 17%	Explore
pericyte	34 studies	57% ± 21%	Explore
CD4-positive, alpha-beta T cell	32 studies	60% ± 17%	Explore
conventional dendritic cell	28 studies	57% ± 17%	Explore
smooth muscle cell	27 studies	57% ± 19%	Explore
classical monocyte	26 studies	53% ± 16%	Explore
regulatory T cell	26 studies	64% ± 16%	Explore
dendritic cell	25 studies	52% ± 24%	Explore
non-classical monocyte	24 studies	57% ± 17%	Explore
endothelial cell of lymphatic vessel	22 studies	55% ± 19%	Explore
plasmacytoid dendritic cell	22 studies	50% ± 15%	Explore
epithelial cell	22 studies	51% ± 21%	Explore
mast cell	21 studies	47% ± 17%	Explore
monocyte	21 studies	47% ± 16%	Explore
plasma cell	21 studies	44% ± 20%	Explore
basal cell	21 studies	54% ± 14%	Explore
mature NK T cell	20 studies	51% ± 18%	Explore
memory B cell	20 studies	59% ± 12%	Explore
naive B cell	20 studies	51% ± 13%	Explore
gamma-delta T cell	19 studies	55% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	56% ± 18%	Explore
connective tissue cell	18 studies	59% ± 17%	Explore
mucosal invariant T cell	16 studies	58% ± 18%	Explore
ciliated cell	16 studies	46% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	51% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	60% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	55% ± 13%	Explore
myeloid cell	15 studies	46% ± 16%	Explore
myofibroblast cell	14 studies	62% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	59% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	58% ± 17%	Explore
capillary endothelial cell	13 studies	48% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	54% ± 18%	Explore
secretory cell	12 studies	48% ± 11%	Explore
endothelial cell of artery	12 studies	49% ± 15%	Explore
vein endothelial cell	12 studies	48% ± 14%	Explore
endothelial cell of vascular tree	12 studies	57% ± 14%	Explore
plasmablast	11 studies	56% ± 17%	Explore
mesothelial cell	10 studies	56% ± 21%	Explore
astrocyte	10 studies	33% ± 18%	Explore
type I pneumocyte	9 studies	42% ± 20%	Explore
type II pneumocyte	9 studies	48% ± 20%	Explore
club cell	9 studies	38% ± 19%	Explore
leukocyte	9 studies	40% ± 10%	Explore
progenitor cell	9 studies	58% ± 18%	Explore
abnormal cell	9 studies	57% ± 15%	Explore
goblet cell	9 studies	34% ± 15%	Explore
T follicular helper cell	9 studies	57% ± 15%	Explore
microglial cell	9 studies	30% ± 13%	Explore
innate lymphoid cell	8 studies	47% ± 12%	Explore
neutrophil	8 studies	28% ± 8%	Explore
oligodendrocyte	8 studies	24% ± 7%	Explore
alveolar macrophage	7 studies	45% ± 16%	Explore
platelet	7 studies	26% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	64% ± 14%	Explore
epithelial cell of proximal tubule	7 studies	35% ± 13%	Explore
neuron	7 studies	46% ± 21%	Explore
IgG plasma cell	7 studies	25% ± 8%	Explore
retinal rod cell	7 studies	35% ± 20%	Explore
precursor B cell	7 studies	56% ± 19%	Explore
ionocyte	6 studies	38% ± 7%	Explore
respiratory goblet cell	6 studies	36% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	70% ± 20%	Explore
mononuclear phagocyte	6 studies	47% ± 15%	Explore
kidney loop of Henle epithelial cell	6 studies	40% ± 9%	Explore
renal alpha-intercalated cell	6 studies	50% ± 12%	Explore
enterocyte	6 studies	34% ± 13%	Explore
intestinal crypt stem cell	6 studies	34% ± 15%	Explore
IgA plasma cell	6 studies	27% ± 7%	Explore
hematopoietic stem cell	6 studies	70% ± 12%	Explore
immature B cell	6 studies	59% ± 21%	Explore
erythrocyte	6 studies	55% ± 21%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	68% ± 16%	Explore
oligodendrocyte precursor cell	6 studies	44% ± 21%	Explore
CD4-positive helper T cell	5 studies	46% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	56% ± 13%	Explore
hematopoietic precursor cell	5 studies	67% ± 18%	Explore
exhausted T cell	5 studies	66% ± 9%	Explore
erythroblast	5 studies	52% ± 24%	Explore
transit amplifying cell	5 studies	31% ± 10%	Explore
lymphocyte	5 studies	58% ± 20%	Explore
pro-B cell	5 studies	62% ± 17%	Explore
T-helper 17 cell	5 studies	64% ± 21%	Explore
cardiac muscle cell	5 studies	25% ± 4%	Explore
double negative thymocyte	5 studies	66% ± 15%	Explore
intermediate monocyte	5 studies	67% ± 20%	Explore
granulocyte	5 studies	59% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	57% ± 17%	Explore
pancreatic A cell	4 studies	63% ± 13%	Explore
type B pancreatic cell	4 studies	67% ± 18%	Explore
glomerular endothelial cell	4 studies	51% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	63% ± 18%	Explore
enteroendocrine cell	4 studies	57% ± 16%	Explore
ON-bipolar cell	4 studies	31% ± 11%	Explore
retinal ganglion cell	4 studies	49% ± 28%	Explore
retinal cone cell	4 studies	60% ± 23%	Explore
brush cell	4 studies	27% ± 13%	Explore
amacrine cell	4 studies	51% ± 22%	Explore
retina horizontal cell	4 studies	47% ± 17%	Explore
retinal pigment epithelial cell	4 studies	43% ± 21%	Explore
adventitial cell	4 studies	56% ± 14%	Explore
adipocyte	4 studies	23% ± 6%	Explore
glial cell	4 studies	45% ± 25%	Explore
acinar cell	4 studies	52% ± 24%	Explore
muscle cell	4 studies	46% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	62% ± 14%	Explore
glutamatergic neuron	4 studies	43% ± 13%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	61% ± 27%	Explore
hepatocyte	4 studies	45% ± 30%	Explore
group 3 innate lymphoid cell	4 studies	63% ± 9%	Explore
T-helper 1 cell	4 studies	69% ± 15%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	64% ± 16%	Explore
duct epithelial cell	3 studies	34% ± 8%	Explore
precursor cell	3 studies	79% ± 9%	Explore
squamous epithelial cell	3 studies	42% ± 25%	Explore
pancreatic D cell	3 studies	58% ± 12%	Explore
monocyte-derived dendritic cell	3 studies	53% ± 24%	Explore
neural crest cell	3 studies	70% ± 16%	Explore
retinal bipolar neuron	3 studies	57% ± 21%	Explore
OFF-bipolar cell	3 studies	36% ± 7%	Explore
glycinergic amacrine cell	3 studies	30% ± 11%	Explore
thymocyte	3 studies	50% ± 29%	Explore
extravillous trophoblast	3 studies	60% ± 13%	Explore
placental villous trophoblast	3 studies	48% ± 13%	Explore
neuroendocrine cell	3 studies	49% ± 20%	Explore
Schwann cell	3 studies	60% ± 28%	Explore
serous secreting cell	3 studies	39% ± 9%	Explore
tissue-resident macrophage	3 studies	31% ± 12%	Explore
intraepithelial lymphocyte	3 studies	52% ± 12%	Explore
Mueller cell	3 studies	56% ± 5%	Explore
rod bipolar cell	3 studies	46% ± 18%	Explore
germinal center B cell	3 studies	49% ± 7%	Explore
myoepithelial cell	3 studies	65% ± 14%	Explore
inflammatory macrophage	3 studies	25% ± 6%	Explore
luminal cell of prostate epithelium	3 studies	37% ± 9%	Explore
GABAergic neuron	3 studies	42% ± 3%	Explore
pancreatic ductal cell	3 studies	62% ± 13%	Explore
melanocyte	3 studies	45% ± 12%	Explore
keratinocyte	3 studies	61% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	69% ± 15%	Explore
double-positive, alpha-beta thymocyte	3 studies	77% ± 6%	Explore
interneuron	3 studies	37% ± 13%	Explore
progenitor cell of mammary luminal epithelium	3 studies	58% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	59% ± 15%	Explore
lung	19 studies	49% ± 17%	Explore
intestine	11 studies	42% ± 17%	Explore
brain	11 studies	34% ± 11%	Explore
eye	10 studies	40% ± 19%	Explore
kidney	9 studies	44% ± 17%	Explore
lymph node	6 studies	56% ± 19%	Explore
bone marrow	6 studies	34% ± 16%	Explore
liver	6 studies	41% ± 18%	Explore
pancreas	5 studies	56% ± 22%	Explore
uterus	5 studies	58% ± 11%	Explore
placenta	4 studies	45% ± 13%	Explore
heart	4 studies	25% ± 5%	Explore
adipose	4 studies	28% ± 16%	Explore
prostate	4 studies	48% ± 10%	Explore
breast	4 studies	56% ± 6%	Explore
adrenal gland	3 studies	50% ± 9%	Explore
esophagus	3 studies	54% ± 27%	Explore
skin	3 studies	49% ± 17%	Explore
thymus	3 studies	66% ± 24%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	21217.40	459 / 459	100%	336.35	1118 / 1118
esophagus	100%	18192.66	1445 / 1445	100%	295.91	183 / 183
intestine	100%	19093.32	966 / 966	100%	279.05	527 / 527
liver	100%	11896.10	226 / 226	100%	185.91	406 / 406
ovary	100%	23744.92	180 / 180	100%	309.19	430 / 430
pancreas	100%	12584.72	328 / 328	100%	257.39	178 / 178
prostate	100%	18278.31	245 / 245	100%	411.46	502 / 502
stomach	100%	15433.79	359 / 359	100%	248.66	286 / 286
thymus	100%	16502.14	653 / 653	100%	358.70	605 / 605
uterus	100%	22568.33	170 / 170	100%	367.56	459 / 459
lung	100%	19423.15	577 / 578	100%	356.47	1155 / 1155
bladder	100%	23504.71	21 / 21	100%	292.96	503 / 504
kidney	100%	13929.09	89 / 89	100%	239.88	897 / 901
skin	100%	19625.45	1808 / 1809	100%	301.35	470 / 472
brain	99%	11866.79	2624 / 2642	100%	324.71	705 / 705
adrenal gland	100%	20040.25	258 / 258	99%	245.27	228 / 230
adipose	100%	21290.48	1204 / 1204	0%	0	0 / 0
blood vessel	100%	23961.86	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	316.64	29 / 29
muscle	100%	49273.52	803 / 803	0%	0	0 / 0
spleen	100%	13270.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	417.55	45 / 45
ureter	0%	0	0 / 0	100%	113.56	1 / 1
heart	98%	18693.05	845 / 861	0%	0	0 / 0
peripheral blood	97%	14060.32	897 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	96%	166.31	77 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_2000767	Biological process	positive regulation of cytoplasmic translation
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0071919	Biological process	G-quadruplex DNA formation
GO_0042632	Biological process	cholesterol homeostasis
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003727	Molecular function	single-stranded RNA binding
GO_0045182	Molecular function	translation regulator activity
GO_0003729	Molecular function	mRNA binding
GO_0051880	Molecular function	G-quadruplex DNA binding
GO_0008270	Molecular function	zinc ion binding
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CNBP
Protein name	CCHC-type zinc finger nucleic acid binding protein isoform 2 CCHC-type zinc finger nucleic acid binding protein (Cellular nucleic acid-binding protein) (CNBP) (Zinc finger protein 9) CCHC-type zinc finger nucleic acid binding protein (Cellular nucleic acid-binding protein) (Zinc finger protein 9) CCHC-type zinc finger nucleic acid binding protein
Synonyms	ZNF9 RNF163
Description	FUNCTION: Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression . Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity). .; FUNCTION: [Isoform 1]: Binds G-rich elements in target mRNA coding sequences . Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs . .; FUNCTION: [Isoform 2]: Binds to RNA. .; FUNCTION: [Isoform 4]: Binds to RNA. .; FUNCTION: [Isoform 5]: Binds to RNA. .; FUNCTION: [Isoform 6]: Binds to RNA. .; FUNCTION: [Isoform 8]: Binds to RNA. .
Accessions	ENST00000441626.6 [P62633-6] ENST00000504813.5 [P62633-3] P62633 ENST00000422453.7 [P62633-1] ENST00000451728.6 [P62633-4] D6RAT4 ENST00000512338.1 A0A0S2Z4Q3 ENST00000446936.6 [P62633-5] A0A0S2Z4K2 A0A0S2Z4P7 ENST00000500450.6 [P62633-7] ENST00000502976.5 [P62633-2]

CNBP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review