CLIC1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	43 studies	59% ± 18%	Explore
natural killer cell	42 studies	71% ± 19%	Explore
macrophage	39 studies	68% ± 22%	Explore
endothelial cell	38 studies	57% ± 24%	Explore
CD8-positive, alpha-beta T cell	38 studies	60% ± 21%	Explore
fibroblast	35 studies	54% ± 18%	Explore
T cell	32 studies	59% ± 20%	Explore
pericyte	30 studies	63% ± 19%	Explore
CD4-positive, alpha-beta T cell	30 studies	57% ± 19%	Explore
conventional dendritic cell	29 studies	81% ± 16%	Explore
classical monocyte	27 studies	78% ± 14%	Explore
dendritic cell	26 studies	63% ± 26%	Explore
mast cell	26 studies	70% ± 22%	Explore
regulatory T cell	26 studies	66% ± 18%	Explore
smooth muscle cell	25 studies	51% ± 16%	Explore
monocyte	24 studies	67% ± 24%	Explore
non-classical monocyte	24 studies	84% ± 13%	Explore
plasmacytoid dendritic cell	23 studies	72% ± 13%	Explore
plasma cell	22 studies	60% ± 22%	Explore
mature NK T cell	22 studies	65% ± 18%	Explore
epithelial cell	22 studies	72% ± 19%	Explore
memory B cell	20 studies	68% ± 15%	Explore
endothelial cell of lymphatic vessel	19 studies	63% ± 15%	Explore
gamma-delta T cell	19 studies	67% ± 15%	Explore
basal cell	19 studies	70% ± 16%	Explore
ciliated cell	18 studies	74% ± 20%	Explore
naive B cell	18 studies	56% ± 11%	Explore
connective tissue cell	18 studies	55% ± 19%	Explore
mucosal invariant T cell	16 studies	61% ± 15%	Explore
capillary endothelial cell	16 studies	54% ± 25%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	69% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	72% ± 20%	Explore
myeloid cell	15 studies	66% ± 25%	Explore
neutrophil	14 studies	55% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	36% ± 11%	Explore
endothelial cell of artery	13 studies	56% ± 20%	Explore
myofibroblast cell	13 studies	52% ± 16%	Explore
innate lymphoid cell	12 studies	67% ± 15%	Explore
plasmablast	12 studies	72% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	61% ± 23%	Explore
secretory cell	12 studies	74% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	55% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	56% ± 24%	Explore
vein endothelial cell	11 studies	66% ± 16%	Explore
endothelial cell of vascular tree	11 studies	73% ± 14%	Explore
platelet	10 studies	51% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	54% ± 21%	Explore
progenitor cell	10 studies	72% ± 20%	Explore
abnormal cell	10 studies	55% ± 19%	Explore
goblet cell	10 studies	59% ± 21%	Explore
mesothelial cell	10 studies	53% ± 17%	Explore
T follicular helper cell	9 studies	49% ± 15%	Explore
hematopoietic stem cell	9 studies	74% ± 28%	Explore
type I pneumocyte	8 studies	54% ± 15%	Explore
type II pneumocyte	8 studies	52% ± 23%	Explore
leukocyte	8 studies	69% ± 9%	Explore
IgG plasma cell	8 studies	35% ± 20%	Explore
brush cell	8 studies	47% ± 20%	Explore
alveolar macrophage	7 studies	67% ± 28%	Explore
club cell	7 studies	76% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	76% ± 22%	Explore
mononuclear phagocyte	7 studies	64% ± 24%	Explore
epithelial cell of proximal tubule	7 studies	46% ± 20%	Explore
enterocyte	7 studies	59% ± 17%	Explore
IgA plasma cell	7 studies	41% ± 21%	Explore
hematopoietic precursor cell	6 studies	66% ± 26%	Explore
respiratory goblet cell	6 studies	67% ± 24%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	74% ± 28%	Explore
kidney loop of Henle epithelial cell	6 studies	53% ± 11%	Explore
renal alpha-intercalated cell	6 studies	50% ± 11%	Explore
megakaryocyte	6 studies	84% ± 11%	Explore
intermediate monocyte	6 studies	75% ± 26%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	63% ± 18%	Explore
erythrocyte	6 studies	46% ± 11%	Explore
CD4-positive helper T cell	5 studies	47% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	68% ± 13%	Explore
exhausted T cell	5 studies	85% ± 8%	Explore
ionocyte	5 studies	58% ± 13%	Explore
enteroendocrine cell	5 studies	62% ± 27%	Explore
transit amplifying cell	5 studies	60% ± 27%	Explore
precursor B cell	5 studies	63% ± 13%	Explore
neuroendocrine cell	5 studies	64% ± 17%	Explore
T-helper 17 cell	5 studies	72% ± 19%	Explore
group 3 innate lymphoid cell	5 studies	81% ± 7%	Explore
immature B cell	5 studies	72% ± 13%	Explore
double negative thymocyte	5 studies	69% ± 14%	Explore
granulocyte	5 studies	78% ± 24%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	64% ± 29%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	53% ± 16%	Explore
deuterosomal cell	4 studies	54% ± 21%	Explore
duct epithelial cell	4 studies	81% ± 5%	Explore
squamous epithelial cell	4 studies	39% ± 26%	Explore
pancreatic A cell	4 studies	64% ± 19%	Explore
type B pancreatic cell	4 studies	58% ± 20%	Explore
glomerular endothelial cell	4 studies	48% ± 12%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	68% ± 9%	Explore
intestinal crypt stem cell	4 studies	72% ± 12%	Explore
erythroblast	4 studies	39% ± 11%	Explore
pro-B cell	4 studies	63% ± 14%	Explore
neuron	4 studies	38% ± 7%	Explore
microglial cell	4 studies	61% ± 15%	Explore
adventitial cell	4 studies	57% ± 9%	Explore
mucus secreting cell	4 studies	64% ± 12%	Explore
inflammatory macrophage	4 studies	49% ± 11%	Explore
germinal center B cell	4 studies	53% ± 21%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	76% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	74% ± 28%	Explore
T-helper 1 cell	4 studies	74% ± 15%	Explore
precursor cell	3 studies	82% ± 6%	Explore
pancreatic D cell	3 studies	69% ± 21%	Explore
monocyte-derived dendritic cell	3 studies	81% ± 19%	Explore
podocyte	3 studies	52% ± 1%	Explore
neural crest cell	3 studies	45% ± 14%	Explore
renal principal cell	3 studies	53% ± 10%	Explore
thymocyte	3 studies	47% ± 30%	Explore
extravillous trophoblast	3 studies	89% ± 7%	Explore
placental villous trophoblast	3 studies	80% ± 10%	Explore
lymphocyte	3 studies	77% ± 10%	Explore
serous secreting cell	3 studies	43% ± 13%	Explore
tissue-resident macrophage	3 studies	54% ± 25%	Explore
intraepithelial lymphocyte	3 studies	80% ± 2%	Explore
acinar cell	3 studies	35% ± 17%	Explore
endothelial cell of sinusoid	3 studies	36% ± 5%	Explore
muscle cell	3 studies	44% ± 25%	Explore
myoepithelial cell	3 studies	56% ± 3%	Explore
luminal cell of prostate epithelium	3 studies	73% ± 5%	Explore
IgM plasma cell	3 studies	46% ± 20%	Explore
pancreatic ductal cell	3 studies	81% ± 2%	Explore
glial cell	3 studies	37% ± 10%	Explore
keratinocyte	3 studies	71% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	55% ± 13%	Explore
progenitor cell of mammary luminal epithelium	3 studies	72% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	63% ± 12%	Explore
lung	18 studies	62% ± 17%	Explore
intestine	12 studies	49% ± 17%	Explore
kidney	9 studies	56% ± 20%	Explore
bone marrow	6 studies	39% ± 23%	Explore
liver	6 studies	44% ± 19%	Explore
pancreas	5 studies	53% ± 25%	Explore
placenta	5 studies	61% ± 30%	Explore
uterus	5 studies	63% ± 25%	Explore
lymph node	5 studies	64% ± 14%	Explore
prostate	4 studies	65% ± 13%	Explore
breast	4 studies	67% ± 6%	Explore
heart	3 studies	27% ± 10%	Explore
adrenal gland	3 studies	57% ± 21%	Explore
esophagus	3 studies	54% ± 20%	Explore
skin	3 studies	55% ± 21%	Explore
thymus	3 studies	61% ± 29%	Explore
brain	3 studies	48% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	11878.89	966 / 966	100%	1084.84	527 / 527
ovary	100%	7179.65	180 / 180	100%	488.70	430 / 430
skin	100%	18481.72	1809 / 1809	100%	703.62	472 / 472
stomach	100%	9691.87	359 / 359	100%	875.24	286 / 286
esophagus	100%	12422.42	1444 / 1445	100%	470.29	183 / 183
prostate	100%	11283.39	245 / 245	100%	642.93	501 / 502
uterus	100%	10654.34	170 / 170	100%	782.34	458 / 459
lung	100%	16796.63	578 / 578	100%	665.64	1152 / 1155
thymus	100%	9712.95	652 / 653	100%	569.27	604 / 605
breast	100%	13055.83	459 / 459	99%	600.52	1112 / 1118
bladder	100%	13096.57	21 / 21	99%	812.02	501 / 504
kidney	100%	14102.84	89 / 89	97%	570.43	873 / 901
adrenal gland	100%	7530.41	258 / 258	94%	313.22	217 / 230
pancreas	87%	4034.55	284 / 328	99%	889.59	177 / 178
liver	54%	2129.10	121 / 226	87%	310.57	353 / 406
adipose	100%	14500.37	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	797.80	29 / 29
spleen	100%	15619.19	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	728.69	45 / 45
ureter	0%	0	0 / 0	100%	456.73	1 / 1
blood vessel	100%	14015.08	1334 / 1335	0%	0	0 / 0
peripheral blood	100%	37549.58	928 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	349.43	79 / 80
heart	94%	5679.86	811 / 861	0%	0	0 / 0
brain	19%	691.69	496 / 2642	43%	158.93	304 / 705
muscle	14%	448.41	111 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0