UPK1A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of UPK1A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UPK1A at tissue level.

III. Associated gene sets

GO_0030855Biological processepithelial cell differentiation
GO_0009986Cellular componentcell surface
GO_0070062Cellular componentextracellular exosome
GO_0032991Cellular componentprotein-containing complex
GO_0120001Cellular componentapical plasma membrane urothelial plaque
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUPK1A
Protein nameUroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa)
SynonymsTSPAN21
DescriptionFUNCTION: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). .

AccessionsENST00000379013.6 [O00322-2]
ENST00000222275.3 [O00322-1]
O00322