Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 23 studies | 28% ± 15% | |
macrophage | 21 studies | 34% ± 15% | |
astrocyte | 17 studies | 35% ± 14% | |
endothelial cell | 16 studies | 34% ± 19% | |
ciliated cell | 15 studies | 29% ± 13% | |
microglial cell | 13 studies | 40% ± 16% | |
pericyte | 11 studies | 26% ± 15% | |
connective tissue cell | 9 studies | 30% ± 19% | |
oligodendrocyte precursor cell | 9 studies | 29% ± 13% | |
myeloid cell | 9 studies | 26% ± 8% | |
epithelial cell | 9 studies | 31% ± 16% | |
monocyte | 8 studies | 25% ± 10% | |
dendritic cell | 7 studies | 24% ± 10% | |
conventional dendritic cell | 6 studies | 21% ± 5% | |
basal cell | 6 studies | 33% ± 11% | |
smooth muscle cell | 6 studies | 19% ± 3% | |
adipocyte | 6 studies | 30% ± 16% | |
type II pneumocyte | 6 studies | 23% ± 5% | |
abnormal cell | 5 studies | 38% ± 17% | |
cardiac muscle cell | 5 studies | 43% ± 9% | |
mesothelial cell | 5 studies | 22% ± 3% | |
Mueller cell | 5 studies | 32% ± 10% | |
oligodendrocyte | 5 studies | 26% ± 6% | |
classical monocyte | 4 studies | 21% ± 5% | |
progenitor cell | 4 studies | 20% ± 2% | |
epithelial cell of proximal tubule | 4 studies | 22% ± 6% | |
myofibroblast cell | 4 studies | 25% ± 5% | |
retinal cone cell | 4 studies | 29% ± 15% | |
GABAergic neuron | 4 studies | 42% ± 15% | |
glutamatergic neuron | 4 studies | 52% ± 17% | |
endothelial cell of lymphatic vessel | 4 studies | 24% ± 7% | |
interneuron | 4 studies | 32% ± 16% | |
mast cell | 4 studies | 18% ± 2% | |
non-classical monocyte | 3 studies | 21% ± 6% | |
glial cell | 3 studies | 28% ± 8% | |
extravillous trophoblast | 3 studies | 43% ± 21% | |
club cell | 3 studies | 20% ± 4% | |
retinal pigment epithelial cell | 3 studies | 33% ± 12% | |
tissue-resident macrophage | 3 studies | 25% ± 2% | |
lymphocyte | 3 studies | 22% ± 4% | |
amacrine cell | 3 studies | 33% ± 12% | |
retina horizontal cell | 3 studies | 35% ± 11% | |
chondrocyte | 3 studies | 33% ± 11% | |
hepatocyte | 3 studies | 45% ± 32% | |
ependymal cell | 3 studies | 47% ± 19% | |
adventitial cell | 3 studies | 21% ± 3% | |
alveolar macrophage | 3 studies | 28% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 4280.54 | 180 / 180 | 100% | 84.67 | 428 / 430 |
breast | 100% | 2574.00 | 459 / 459 | 99% | 101.59 | 1112 / 1118 |
prostate | 100% | 2067.86 | 244 / 245 | 99% | 64.47 | 496 / 502 |
lung | 100% | 2977.45 | 576 / 578 | 98% | 121.38 | 1137 / 1155 |
uterus | 100% | 2675.71 | 170 / 170 | 98% | 89.86 | 448 / 459 |
bladder | 100% | 2879.05 | 21 / 21 | 97% | 87.76 | 491 / 504 |
skin | 99% | 5449.00 | 1791 / 1809 | 97% | 96.04 | 458 / 472 |
thymus | 99% | 2005.63 | 648 / 653 | 96% | 42.15 | 581 / 605 |
intestine | 100% | 1991.64 | 964 / 966 | 94% | 66.37 | 497 / 527 |
kidney | 100% | 2155.49 | 89 / 89 | 93% | 121.84 | 842 / 901 |
brain | 94% | 1485.41 | 2492 / 2642 | 99% | 58.83 | 698 / 705 |
stomach | 100% | 1946.92 | 359 / 359 | 92% | 51.82 | 262 / 286 |
pancreas | 94% | 1285.46 | 307 / 328 | 97% | 80.15 | 173 / 178 |
esophagus | 94% | 1517.09 | 1352 / 1445 | 91% | 55.32 | 166 / 183 |
liver | 91% | 3198.02 | 205 / 226 | 85% | 59.95 | 344 / 406 |
adrenal gland | 100% | 2818.23 | 258 / 258 | 63% | 43.95 | 145 / 230 |
muscle | 100% | 8393.05 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1781.73 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 62.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 46.50 | 1 / 1 |
adipose | 100% | 3249.21 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3209.70 | 1329 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 3261.26 | 847 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 39.90 | 27 / 29 |
peripheral blood | 90% | 4313.85 | 837 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 66.17 | 72 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0018401 | Biological process | peptidyl-proline hydroxylation to 4-hydroxy-L-proline |
GO_0030199 | Biological process | collagen fibril organization |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016222 | Cellular component | procollagen-proline 4-dioxygenase complex |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005506 | Molecular function | iron ion binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0031418 | Molecular function | L-ascorbic acid binding |
GO_0005515 | Molecular function | protein binding |
GO_0004656 | Molecular function | procollagen-proline 4-dioxygenase activity |
Gene name | P4HA1 |
Protein name | Prolyl 4-hydroxylase subunit alpha-1 (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) |
Synonyms | hCG_19276 P4HA |
Description | FUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. . FUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. . |
Accessions | ENST00000440381.5 [P13674-3] ENST00000263556.3 [P13674-2] Q5VSQ6 ENST00000373008.7 [P13674-2] P13674 ENST00000307116.6 [P13674-1] ENST00000394890.7 [P13674-1] |