P4HA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0018401Biological processpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO_0030199Biological processcollagen fibril organization
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005783Cellular componentendoplasmic reticulum
GO_0016222Cellular componentprocollagen-proline 4-dioxygenase complex
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0005506Molecular functioniron ion binding
GO_0042802Molecular functionidentical protein binding
GO_0031418Molecular functionL-ascorbic acid binding
GO_0005515Molecular functionprotein binding
GO_0004656Molecular functionprocollagen-proline 4-dioxygenase activity

IV. Literature review

[source]
Gene nameP4HA1
Protein nameProlyl 4-hydroxylase subunit alpha-1 (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)
SynonymshCG_19276
P4HA
DescriptionFUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. .

FUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. .

AccessionsENST00000440381.5 [P13674-3]
ENST00000263556.3 [P13674-2]
Q5VSQ6
ENST00000373008.7 [P13674-2]
P13674
ENST00000307116.6 [P13674-1]
ENST00000394890.7 [P13674-1]