RPS23 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034063Biological processstress granule assembly
GO_0006412Biological processtranslation
GO_0042274Biological processribosomal small subunit biogenesis
GO_1990145Biological processmaintenance of translational fidelity
GO_0002181Biological processcytoplasmic translation
GO_0005730Cellular componentnucleolus
GO_0022626Cellular componentcytosolic ribosome
GO_0022627Cellular componentcytosolic small ribosomal subunit
GO_0005840Cellular componentribosome
GO_0016020Cellular componentmembrane
GO_0032040Cellular componentsmall-subunit processome
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0005737Cellular componentcytoplasm
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0003735Molecular functionstructural constituent of ribosome
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRPS23
Protein nameRibosomal protein S23
Small ribosomal subunit protein uS12 (40S ribosomal protein S23)
SynonymshCG_38189
DescriptionFUNCTION: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules . The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain . The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel . Plays an important role in translational accuracy . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . .

AccessionsENST00000510210.5
D6RDJ2
ENST00000651545.1
ENST00000507980.1
D6RD47
A8K517
ENST00000512493.5
ENST00000510019.5
P62266
D6R9I7
D6RIX0
ENST00000511844.1
ENST00000296674.13