Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 25% ± 7% | |
microglial cell | 6 studies | 21% ± 5% | |
neuron | 5 studies | 25% ± 8% | |
epithelial cell | 5 studies | 32% ± 7% | |
astrocyte | 5 studies | 27% ± 8% | |
retinal ganglion cell | 4 studies | 46% ± 26% | |
fibroblast | 4 studies | 20% ± 2% | |
ciliated cell | 4 studies | 20% ± 4% | |
endothelial cell of lymphatic vessel | 4 studies | 21% ± 3% | |
GABAergic neuron | 4 studies | 41% ± 14% | |
macrophage | 4 studies | 23% ± 5% | |
oligodendrocyte | 4 studies | 26% ± 4% | |
type I pneumocyte | 3 studies | 19% ± 4% | |
glutamatergic neuron | 3 studies | 59% ± 10% | |
oligodendrocyte precursor cell | 3 studies | 26% ± 7% | |
basal cell | 3 studies | 29% ± 7% | |
transit amplifying cell | 3 studies | 30% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 6251.45 | 2642 / 2642 | 100% | 36.32 | 705 / 705 |
ovary | 100% | 3911.18 | 180 / 180 | 100% | 20.66 | 430 / 430 |
prostate | 100% | 3894.48 | 245 / 245 | 100% | 25.73 | 502 / 502 |
stomach | 100% | 3385.41 | 359 / 359 | 100% | 32.02 | 286 / 286 |
breast | 100% | 3399.18 | 459 / 459 | 100% | 34.15 | 1116 / 1118 |
intestine | 100% | 4956.78 | 966 / 966 | 100% | 31.17 | 526 / 527 |
bladder | 100% | 4109.10 | 21 / 21 | 100% | 23.85 | 503 / 504 |
esophagus | 100% | 4335.35 | 1442 / 1445 | 100% | 28.31 | 183 / 183 |
thymus | 100% | 5849.88 | 653 / 653 | 100% | 24.65 | 603 / 605 |
kidney | 100% | 4336.03 | 89 / 89 | 100% | 24.71 | 898 / 901 |
uterus | 100% | 4122.26 | 170 / 170 | 100% | 24.55 | 457 / 459 |
lung | 99% | 3154.96 | 575 / 578 | 100% | 23.72 | 1155 / 1155 |
skin | 100% | 2968.30 | 1807 / 1809 | 99% | 32.01 | 465 / 472 |
adrenal gland | 100% | 6481.99 | 258 / 258 | 98% | 31.13 | 226 / 230 |
liver | 100% | 3052.25 | 225 / 226 | 98% | 14.21 | 399 / 406 |
pancreas | 98% | 2290.54 | 322 / 328 | 99% | 19.41 | 176 / 178 |
adipose | 100% | 3206.13 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4722.95 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.91 | 29 / 29 |
muscle | 100% | 7080.92 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2980.85 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 23.27 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.10 | 1 / 1 |
heart | 98% | 3460.31 | 848 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 20.16 | 78 / 80 |
peripheral blood | 68% | 1237.72 | 633 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0090114 | Biological process | COPII-coated vesicle budding |
GO_0090158 | Biological process | endoplasmic reticulum membrane organization |
GO_0007029 | Biological process | endoplasmic reticulum organization |
GO_0061817 | Biological process | endoplasmic reticulum-plasma membrane tethering |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0045070 | Biological process | positive regulation of viral genome replication |
GO_0030968 | Biological process | endoplasmic reticulum unfolded protein response |
GO_0036498 | Biological process | IRE1-mediated unfolded protein response |
GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
GO_0030301 | Biological process | cholesterol transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0070971 | Cellular component | endoplasmic reticulum exit site |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005737 | Cellular component | cytoplasm |
GO_0019899 | Molecular function | enzyme binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0048487 | Molecular function | beta-tubulin binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0033149 | Molecular function | FFAT motif binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | VAPB |
Protein name | Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C) VAMP (Vesicle-associated membrane protein)-associated protein B and C (cDNA FLJ13179 fis, clone NT2RP3003918, highly similar to Vesicle-associated membrane protein-associated protein B/C) VAMP associated protein B and C |
Synonyms | hCG_26693 UNQ484/PRO983 |
Description | FUNCTION: Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44 . Interacts with STARD3 in a FFAT motif phosphorylation dependent manner . Via interaction with WDR44 participates in neosynthesized protein export . Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity . Involved in cellular calcium homeostasis regulation . . |
Accessions | Q53XM7 ENST00000395802.7 [O95292-2] E5RK64 ENST00000475243.6 [O95292-1] ENST00000520497.1 O95292 |