Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 13 studies | 22% ± 7% | |
endothelial cell | 10 studies | 24% ± 7% | |
pericyte | 7 studies | 17% ± 1% | |
enterocyte | 6 studies | 22% ± 3% | |
endothelial cell of artery | 6 studies | 24% ± 5% | |
epithelial cell | 5 studies | 43% ± 20% | |
basal cell | 5 studies | 28% ± 12% | |
connective tissue cell | 5 studies | 20% ± 3% | |
pancreatic A cell | 4 studies | 34% ± 24% | |
plasma cell | 4 studies | 29% ± 12% | |
goblet cell | 4 studies | 26% ± 9% | |
adipocyte | 4 studies | 21% ± 5% | |
ionocyte | 3 studies | 26% ± 6% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 3% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 23% ± 5% | |
glomerular endothelial cell | 3 studies | 23% ± 1% | |
ciliated cell | 3 studies | 33% ± 6% | |
gamma-delta T cell | 3 studies | 21% ± 3% | |
type I pneumocyte | 3 studies | 22% ± 3% | |
GABAergic neuron | 3 studies | 33% ± 5% | |
glutamatergic neuron | 3 studies | 45% ± 6% | |
oligodendrocyte | 3 studies | 18% ± 3% | |
astrocyte | 3 studies | 17% ± 0% | |
interneuron | 3 studies | 29% ± 11% | |
hepatocyte | 3 studies | 39% ± 30% | |
oligodendrocyte precursor cell | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5436.93 | 1445 / 1445 | 100% | 44.99 | 183 / 183 |
liver | 100% | 4555.39 | 226 / 226 | 100% | 60.37 | 406 / 406 |
ovary | 100% | 4061.48 | 180 / 180 | 100% | 42.49 | 430 / 430 |
pancreas | 100% | 3084.03 | 328 / 328 | 100% | 55.14 | 178 / 178 |
stomach | 100% | 4760.38 | 359 / 359 | 100% | 49.48 | 286 / 286 |
uterus | 100% | 4492.14 | 170 / 170 | 100% | 57.46 | 459 / 459 |
breast | 100% | 7744.33 | 459 / 459 | 100% | 90.61 | 1117 / 1118 |
kidney | 100% | 3739.35 | 89 / 89 | 100% | 83.64 | 900 / 901 |
thymus | 100% | 4902.75 | 653 / 653 | 100% | 81.08 | 604 / 605 |
lung | 100% | 4137.49 | 577 / 578 | 100% | 49.41 | 1155 / 1155 |
bladder | 100% | 5518.10 | 21 / 21 | 100% | 59.29 | 503 / 504 |
intestine | 100% | 5075.69 | 966 / 966 | 100% | 47.52 | 525 / 527 |
prostate | 100% | 3855.16 | 244 / 245 | 100% | 68.48 | 502 / 502 |
skin | 100% | 8934.32 | 1809 / 1809 | 99% | 64.48 | 469 / 472 |
adrenal gland | 100% | 4947.90 | 258 / 258 | 99% | 72.08 | 228 / 230 |
brain | 98% | 2539.56 | 2592 / 2642 | 100% | 45.38 | 705 / 705 |
adipose | 100% | 7943.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5645.98 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 63.36 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.69 | 29 / 29 |
spleen | 100% | 2682.85 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 45.61 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 92.96 | 1 / 1 |
heart | 97% | 3021.43 | 835 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 1755.41 | 766 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 39% | 879.45 | 362 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060612 | Biological process | adipose tissue development |
GO_0015886 | Biological process | heme transport |
GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
GO_0005635 | Cellular component | nuclear envelope |
GO_0012505 | Cellular component | endomembrane system |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005576 | Cellular component | extracellular region |
GO_0016020 | Cellular component | membrane |
GO_0015232 | Molecular function | heme transmembrane transporter activity |
GO_0020037 | Molecular function | heme binding |
GO_0005515 | Molecular function | protein binding |
GO_0005496 | Molecular function | steroid binding |
GO_0003707 | Molecular function | nuclear steroid receptor activity |
Gene name | PGRMC2 |
Protein name | Progesterone receptor membrane component 2 Membrane-associated progesterone receptor component 2 (Progesterone membrane-binding protein) (Steroid receptor protein DG6) |
Synonyms | DG6 hCG_16401 PMBP |
Description | FUNCTION: Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity). May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity). Plays a role in adipocyte function and systemic glucose homeostasis . In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity). . |
Accessions | ENST00000509070.1 U3KQM0 U3KPU8 ENST00000520121.6 [O15173-1] O15173 ENST00000503872.1 ENST00000296425.10 [O15173-1] U3KQ70 ENST00000503588.1 ENST00000512483.5 ENST00000613358.4 [O15173-2] ENST00000394276.3 |