Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 59% ± 17% | |
astrocyte | 13 studies | 24% ± 7% | |
type II pneumocyte | 11 studies | 44% ± 22% | |
macrophage | 9 studies | 27% ± 7% | |
alveolar macrophage | 7 studies | 28% ± 5% | |
endothelial cell | 6 studies | 30% ± 20% | |
adipocyte | 6 studies | 52% ± 24% | |
oligodendrocyte precursor cell | 6 studies | 25% ± 10% | |
ionocyte | 5 studies | 30% ± 10% | |
retinal ganglion cell | 5 studies | 56% ± 26% | |
epithelial cell | 5 studies | 24% ± 8% | |
pancreatic A cell | 4 studies | 45% ± 23% | |
type B pancreatic cell | 4 studies | 49% ± 29% | |
neuron | 4 studies | 35% ± 17% | |
basal cell | 4 studies | 35% ± 12% | |
retinal pigment epithelial cell | 4 studies | 34% ± 20% | |
abnormal cell | 4 studies | 32% ± 19% | |
ciliated cell | 3 studies | 23% ± 4% | |
secretory cell | 3 studies | 23% ± 7% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 21% ± 3% | |
melanocyte | 3 studies | 28% ± 13% | |
goblet cell | 3 studies | 20% ± 2% | |
hepatocyte | 3 studies | 53% ± 27% | |
microglial cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 58863.40 | 2628 / 2642 | 98% | 814.72 | 694 / 705 |
liver | 92% | 52320.97 | 209 / 226 | 88% | 933.61 | 357 / 406 |
breast | 69% | 66305.58 | 315 / 459 | 87% | 515.05 | 970 / 1118 |
adrenal gland | 99% | 33151.62 | 255 / 258 | 55% | 217.61 | 126 / 230 |
lung | 56% | 13683.87 | 322 / 578 | 86% | 317.20 | 991 / 1155 |
skin | 42% | 9329.66 | 753 / 1809 | 94% | 468.42 | 444 / 472 |
esophagus | 42% | 10231.92 | 603 / 1445 | 80% | 255.03 | 147 / 183 |
prostate | 32% | 4097.83 | 78 / 245 | 84% | 332.78 | 420 / 502 |
intestine | 26% | 4493.32 | 251 / 966 | 86% | 299.51 | 454 / 527 |
bladder | 29% | 3616.33 | 6 / 21 | 81% | 314.29 | 410 / 504 |
ureter | 0% | 0 | 0 / 0 | 100% | 161.37 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 99% | 374.13 | 79 / 80 |
tonsil | 0% | 0 | 0 / 0 | 93% | 295.52 | 42 / 45 |
ovary | 57% | 7201.14 | 102 / 180 | 35% | 58.90 | 152 / 430 |
adipose | 89% | 138624.58 | 1074 / 1204 | 0% | 0 | 0 / 0 |
uterus | 11% | 1661.52 | 19 / 170 | 78% | 267.11 | 357 / 459 |
stomach | 10% | 3271.29 | 35 / 359 | 77% | 256.17 | 220 / 286 |
pancreas | 6% | 1139.05 | 20 / 328 | 64% | 118.64 | 114 / 178 |
kidney | 2% | 855.84 | 2 / 89 | 67% | 202.59 | 600 / 901 |
lymph node | 0% | 0 | 0 / 0 | 34% | 45.92 | 10 / 29 |
peripheral blood | 19% | 5082.37 | 174 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 15% | 8094.16 | 198 / 1335 | 0% | 0 | 0 / 0 |
heart | 14% | 2794.81 | 118 / 861 | 0% | 0 | 0 / 0 |
thymus | 7% | 2780.61 | 47 / 653 | 3% | 4.65 | 20 / 605 |
spleen | 3% | 267.82 | 8 / 241 | 0% | 0 | 0 / 0 |
muscle | 2% | 316.46 | 20 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006636 | Biological process | unsaturated fatty acid biosynthetic process |
GO_0120162 | Biological process | positive regulation of cold-induced thermogenesis |
GO_1903966 | Biological process | monounsaturated fatty acid biosynthetic process |
GO_0070542 | Biological process | response to fatty acid |
GO_0005730 | Cellular component | nucleolus |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0016491 | Molecular function | oxidoreductase activity |
GO_0005506 | Molecular function | iron ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0032896 | Molecular function | palmitoyl-CoA 9-desaturase activity |
GO_0004768 | Molecular function | stearoyl-CoA 9-desaturase activity |
Gene name | SCD |
Protein name | Stearoyl-CoA desaturase (hSCD1) (EC 1.14.19.1) (Acyl-CoA desaturase) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) |
Synonyms | SCD1 SCDOS FADS5 |
Description | FUNCTION: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates . Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA . Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids . Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). . |
Accessions | ENST00000370355.3 O00767 |