MRAP | OmnibusX

Name	Number of supported studies	Average coverage
adipocyte	3 studies	20% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MRAP at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	669.30	258 / 258	20%	1.29	46 / 230
adipose	93%	167.11	1122 / 1204	0%	0	0 / 0
breast	72%	124.15	330 / 459	2%	0.06	17 / 1118
ovary	27%	8.09	48 / 180	0%	0.00	1 / 430
lung	19%	4.09	112 / 578	1%	0.02	8 / 1155
liver	12%	2.77	27 / 226	5%	0.09	19 / 406
bladder	14%	3.00	3 / 21	1%	0.02	6 / 504
blood vessel	11%	8.69	145 / 1335	0%	0	0 / 0
skin	8%	2.03	147 / 1809	1%	0.02	3 / 472
heart	7%	2.13	58 / 861	0%	0	0 / 0
thymus	5%	1.81	31 / 653	0%	0.00	1 / 605
pancreas	2%	0.47	6 / 328	3%	0.14	5 / 178
intestine	4%	3.19	39 / 966	0%	0.00	1 / 527
esophagus	2%	0.84	35 / 1445	1%	0.01	1 / 183
stomach	2%	1.72	7 / 359	1%	0.01	2 / 286
kidney	1%	1.48	1 / 89	0%	0.01	3 / 901
eye	0%	0	0 / 0	1%	0.03	1 / 80
prostate	0%	0.09	1 / 245	0%	0.01	2 / 502
brain	0%	0.10	8 / 2642	0%	0.01	1 / 705
uterus	0%	0	0 / 170	0%	0.01	2 / 459
peripheral blood	0%	0.04	2 / 929	0%	0	0 / 0
muscle	0%	0.07	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1903077	Biological process	negative regulation of protein localization to plasma membrane
GO_0106070	Biological process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0072659	Biological process	protein localization to plasma membrane
GO_0106072	Biological process	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0106071	Biological process	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030545	Molecular function	signaling receptor regulator activity
GO_0031780	Molecular function	corticotropin hormone receptor binding
GO_0031782	Molecular function	type 4 melanocortin receptor binding
GO_0031783	Molecular function	type 5 melanocortin receptor binding
GO_0042802	Molecular function	identical protein binding
GO_0070996	Molecular function	type 1 melanocortin receptor binding
GO_0005515	Molecular function	protein binding
GO_0031781	Molecular function	type 3 melanocortin receptor binding

Gene name	MRAP
Protein name	Melanocortin-2 receptor accessory protein (B27) (Fat cell-specific low molecular weight protein) (Fat tissue-specific low MW protein)
Synonyms	C21orf61 FALP
Description	FUNCTION: Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells. .
Accessions	ENST00000339944.4 [Q8TCY5-2] Q8TCY5 ENST00000303645.10 [Q8TCY5-4] ENST00000399784.6 [Q8TCY5-4]

MRAP report