SLC35B4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015790Biological processUDP-xylose transmembrane transport
GO_1990569Biological processUDP-N-acetylglucosamine transmembrane transport
GO_0006111Biological processregulation of gluconeogenesis
GO_0000139Cellular componentGolgi membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005794Cellular componentGolgi apparatus
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005464Molecular functionUDP-xylose transmembrane transporter activity
GO_0005462Molecular functionUDP-N-acetylglucosamine transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC35B4
Protein nameNucleotide sugar transporter SLC35B4 (Solute carrier family 35 member B4) (UDP-xylose and UDP-N-acetylglucosamine transporter) (YEA4 homolog)
Solute carrier family 35 member B4
SynonymsPSEC0055
YEA4
DescriptionFUNCTION: Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for another nucleotide sugar. May couple UDP-alpha-D-glucuronate (UDP-GlcA) or UDP-alpha-D-xylose (UDP-Xyl) efflux to UDP-alpha-D-glucuronate (UDP-GlcA) influx into the ER lumen, which in turn stimulates glucuronidation and excretion of endobiotics and xenobiotics. .; FUNCTION: [Isoform 1]: Has UDP-GlcA:UDP-GlcNAc antiporter activity. .; FUNCTION: [Isoform 2]: Has UDP-GlcA:UDP-GlcNAc antiporter activity. .

AccessionsENST00000416907.5
ENST00000470969.2 [Q969S0-2]
Q969S0
ENST00000378509.9 [Q969S0-1]
F8WAW0