I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasma cell | 4 studies | 26% ± 5% | |
| non-classical monocyte | 3 studies | 20% ± 5% | |
| epithelial cell | 3 studies | 30% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| plasma cell | 4 studies | 26% ± 5% | |
| non-classical monocyte | 3 studies | 20% ± 5% | |
| epithelial cell | 3 studies | 30% ± 7% |
Insufficient scRNA-seq data for expression of AGA at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 1117.79 | 653 / 653 | 100% | 45.29 | 603 / 605 |
| pancreas | 100% | 616.77 | 328 / 328 | 99% | 26.09 | 177 / 178 |
| breast | 100% | 856.49 | 458 / 459 | 100% | 40.99 | 1114 / 1118 |
| skin | 100% | 1082.48 | 1808 / 1809 | 99% | 41.76 | 469 / 472 |
| kidney | 100% | 730.78 | 89 / 89 | 99% | 29.86 | 894 / 901 |
| bladder | 100% | 532.05 | 21 / 21 | 99% | 26.04 | 499 / 504 |
| prostate | 100% | 617.10 | 244 / 245 | 99% | 36.73 | 499 / 502 |
| lung | 99% | 711.39 | 574 / 578 | 100% | 36.26 | 1150 / 1155 |
| esophagus | 99% | 725.25 | 1436 / 1445 | 98% | 20.95 | 180 / 183 |
| intestine | 100% | 625.43 | 966 / 966 | 97% | 20.36 | 513 / 527 |
| liver | 100% | 632.51 | 226 / 226 | 97% | 23.53 | 394 / 406 |
| stomach | 100% | 531.45 | 358 / 359 | 97% | 18.04 | 276 / 286 |
| brain | 97% | 545.84 | 2559 / 2642 | 99% | 27.05 | 699 / 705 |
| adrenal gland | 100% | 1017.50 | 258 / 258 | 96% | 31.65 | 220 / 230 |
| uterus | 99% | 631.42 | 169 / 170 | 96% | 25.21 | 441 / 459 |
| ovary | 100% | 716.94 | 180 / 180 | 92% | 14.12 | 395 / 430 |
| adipose | 100% | 693.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 21.02 | 29 / 29 |
| spleen | 100% | 811.94 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 24.17 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.86 | 1 / 1 |
| blood vessel | 100% | 918.85 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 23.11 | 78 / 80 |
| muscle | 95% | 306.17 | 759 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 637.54 | 878 / 929 | 0% | 0 | 0 / 0 |
| heart | 90% | 320.72 | 772 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006517 | Biological process | protein deglycosylation |
| GO_0006508 | Biological process | proteolysis |
| GO_0035578 | Cellular component | azurophil granule lumen |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005764 | Cellular component | lysosome |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0008233 | Molecular function | peptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003948 | Molecular function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| Gene name | AGA |
| Protein name | Aspartylglucosaminidase N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] |
| Synonyms | aspartylglucosaminidase |
| Description | FUNCTION: Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. . |
| Accessions | ENST00000502310.5 ENST00000510635.1 P20933 H0Y9C7 H0Y8L9 ENST00000264595.7 Q16331 |
