CRHBP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CRHBP at tissue level.

III. Associated gene sets

GO_0097211Biological processcellular response to gonadotropin-releasing hormone
GO_0035865Biological processcellular response to potassium ion
GO_0071466Biological processcellular response to xenobiotic stimulus
GO_0006954Biological processinflammatory response
GO_0007611Biological processlearning or memory
GO_0048149Biological processbehavioral response to ethanol
GO_0051459Biological processregulation of corticotropin secretion
GO_0007165Biological processsignal transduction
GO_2000310Biological processregulation of NMDA receptor activity
GO_0071391Biological processcellular response to estrogen stimulus
GO_0071392Biological processcellular response to estradiol stimulus
GO_0051460Biological processnegative regulation of corticotropin secretion
GO_0007565Biological processfemale pregnancy
GO_0071277Biological processcellular response to calcium ion
GO_0045055Biological processregulated exocytosis
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0071320Biological processcellular response to cAMP
GO_0071314Biological processcellular response to cocaine
GO_0009755Biological processhormone-mediated signaling pathway
GO_0001963Biological processsynaptic transmission, dopaminergic
GO_0080135Biological processregulation of cellular response to stress
GO_1900011Biological processnegative regulation of corticotropin-releasing hormone receptor activity
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005874Cellular componentmicrotubule
GO_0043204Cellular componentperikaryon
GO_0043679Cellular componentaxon terminus
GO_0005794Cellular componentGolgi apparatus
GO_0030425Cellular componentdendrite
GO_0043196Cellular componentvaricosity
GO_0005783Cellular componentendoplasmic reticulum
GO_0005767Cellular componentsecondary lysosome
GO_0031045Cellular componentdense core granule
GO_0005771Cellular componentmultivesicular body
GO_0030141Cellular componentsecretory granule
GO_0005634Cellular componentnucleus
GO_0042277Molecular functionpeptide binding
GO_0051424Molecular functioncorticotropin-releasing hormone binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCRHBP
Protein nameCorticotropin-releasing factor-binding protein (Corticotropin-releasing hormone-binding protein)
Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP)
SynonymsCRFBP
DescriptionFUNCTION: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.

FUNCTION: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. .

AccessionsP24387
ENST00000274368.9
ENST00000506501.1
D6RHH7