TSN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006310Biological processDNA recombination
GO_0030422Biological processsiRNA processing
GO_0035194Biological processregulatory ncRNA-mediated post-transcriptional gene silencing
GO_1902555Cellular componentendoribonuclease complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005783Cellular componentendoplasmic reticulum
GO_0001673Cellular componentmale germ cell nucleus
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0004519Molecular functionendonuclease activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003697Molecular functionsingle-stranded DNA binding
GO_0003729Molecular functionmRNA binding
GO_0043565Molecular functionsequence-specific DNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTSN
Protein nameTranslin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO)
Translin (Component 3 of promoter of RISC)
Translin
SynonymshCG_37642
DescriptionFUNCTION: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.; FUNCTION: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.

FUNCTION: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. .; FUNCTION: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. .

FUNCTION: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. .; FUNCTION: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. .

AccessionsENST00000455432.5
H7C1D4
A0A0J9YVW2
ENST00000409193.1
Q15631
ENST00000467324.5
ENST00000490104.5
ENST00000389682.8 [Q15631-1]
E9PGT1
ENST00000478165.5
B3KRM8
A0A0J9YX41
ENST00000536142.5 [Q15631-2]
ENST00000490717.5