PUM3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010835Biological processregulation of protein ADP-ribosylation
GO_0006417Biological processregulation of translation
GO_0005730Cellular componentnucleolus
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene namePUM3
Protein namePumilio RNA binding family member 3
Pumilio homolog 3 (HBV X-transactivated gene 5 protein) (HBV XAg-transactivated protein 5) (Minor histocompatibility antigen HA-8) (HLA-HA8)
KIAA0020 protein
SynonymsXTP5
PUF-A
cPERP-C
KIAA0020
DescriptionFUNCTION: Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress . Binds to double-stranded RNA or DNA without sequence specificity . Involved in development of the eye and of primordial germ cells (By similarity). .

AccessionsENST00000490444.2
Q9NYH5
S4R3K8
Q15397
ENST00000397885.3