Insufficient scRNA-seq data for expression of STEEP1 at single-cell level.
Insufficient scRNA-seq data for expression of STEEP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1262.65 | 459 / 459 | 100% | 39.19 | 1118 / 1118 |
esophagus | 100% | 903.62 | 1445 / 1445 | 100% | 20.75 | 183 / 183 |
lung | 100% | 918.73 | 578 / 578 | 100% | 33.33 | 1155 / 1155 |
ovary | 100% | 1155.01 | 180 / 180 | 100% | 22.48 | 430 / 430 |
brain | 100% | 1039.98 | 2641 / 2642 | 100% | 31.70 | 705 / 705 |
thymus | 100% | 1088.01 | 653 / 653 | 100% | 37.90 | 604 / 605 |
prostate | 100% | 909.38 | 245 / 245 | 100% | 28.34 | 501 / 502 |
intestine | 100% | 1002.26 | 966 / 966 | 100% | 31.21 | 525 / 527 |
bladder | 100% | 958.62 | 21 / 21 | 100% | 34.76 | 502 / 504 |
skin | 100% | 1217.20 | 1809 / 1809 | 100% | 38.86 | 470 / 472 |
uterus | 100% | 1140.54 | 170 / 170 | 100% | 40.67 | 457 / 459 |
stomach | 100% | 741.63 | 359 / 359 | 99% | 26.51 | 284 / 286 |
pancreas | 99% | 528.90 | 325 / 328 | 100% | 27.41 | 178 / 178 |
kidney | 100% | 894.79 | 89 / 89 | 99% | 23.20 | 892 / 901 |
adrenal gland | 100% | 936.52 | 258 / 258 | 98% | 30.15 | 226 / 230 |
liver | 100% | 394.57 | 225 / 226 | 98% | 18.14 | 397 / 406 |
adipose | 100% | 1155.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1176.01 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 46.34 | 29 / 29 |
spleen | 100% | 1028.56 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 36.17 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.55 | 1 / 1 |
muscle | 100% | 703.05 | 800 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 29.20 | 79 / 80 |
heart | 98% | 623.84 | 841 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 89% | 587.35 | 826 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
GO_0032527 | Biological process | protein exit from endoplasmic reticulum |
GO_0090158 | Biological process | endoplasmic reticulum membrane organization |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0044297 | Cellular component | cell body |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | STEEP1 |
Protein name | STING ER exit protein (STEEP) |
Synonyms | CXorf56 |
Description | FUNCTION: Molecular adapter that stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport . Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers . . |
Accessions | ENST00000536133.2 [Q9H5V9-3] ENST00000644802.2 [Q9H5V9-1] ENST00000320339.8 [Q9H5V9-2] Q9H5V9 |