UBE2J2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0006986Biological processresponse to unfolded protein
GO_0085020Biological processprotein K6-linked ubiquitination
GO_1903955Biological processpositive regulation of protein targeting to mitochondrion
GO_0000209Biological processprotein polyubiquitination
GO_0036503Biological processERAD pathway
GO_0000151Cellular componentubiquitin ligase complex
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005634Cellular componentnucleus
GO_0061631Molecular functionubiquitin conjugating enzyme activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameUBE2J2
Protein nameUbiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)
Ubiquitin conjugating enzyme E2 J2
E2 ubiquitin-conjugating enzyme (EC 2.3.2.23)
SynonymsNCUBE2
hCG_20420
DescriptionFUNCTION: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2 . .

AccessionsA6NGS0
ENST00000435198.5
D6RD90
ENST00000400930.8 [Q8N2K1-3]
D6RA15
B1AMF0
ENST00000450390.6
ENST00000488418.2
ENST00000360466.6 [Q8N2K1-1]
ENST00000347370.6
ENST00000473215.5
ENST00000422076.5
ENST00000464036.5
ENST00000477894.5
ENST00000503294.5
ENST00000466752.5
D6REN4
ENST00000349431.11 [Q8N2K1-1]
B1AMF1
D6RC43
ENST00000400929.6
ENST00000502382.1
D6R9H0
D6RB84
ENST00000509720.5
Q8N2K1