Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 22% ± 7% | |
natural killer cell | 7 studies | 20% ± 4% | |
epithelial cell | 6 studies | 33% ± 12% | |
regulatory T cell | 5 studies | 18% ± 3% | |
B cell | 4 studies | 20% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 18% ± 2% | |
CD4-positive, alpha-beta T cell | 4 studies | 18% ± 3% | |
classical monocyte | 4 studies | 26% ± 8% | |
conventional dendritic cell | 4 studies | 28% ± 13% | |
fibroblast | 4 studies | 23% ± 6% | |
pericyte | 4 studies | 19% ± 4% | |
ciliated cell | 4 studies | 28% ± 8% | |
CD8-positive, alpha-beta T cell | 4 studies | 18% ± 4% | |
abnormal cell | 4 studies | 20% ± 3% | |
basal cell | 4 studies | 30% ± 10% | |
plasmacytoid dendritic cell | 4 studies | 21% ± 4% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 2% | |
non-classical monocyte | 3 studies | 30% ± 7% | |
macrophage | 3 studies | 17% ± 2% | |
astrocyte | 3 studies | 19% ± 2% | |
glutamatergic neuron | 3 studies | 33% ± 12% | |
dendritic cell | 3 studies | 33% ± 13% | |
goblet cell | 3 studies | 22% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2857.04 | 1445 / 1445 | 100% | 27.95 | 183 / 183 |
lung | 100% | 2539.58 | 578 / 578 | 100% | 34.18 | 1155 / 1155 |
ovary | 100% | 2328.98 | 180 / 180 | 100% | 43.64 | 430 / 430 |
pancreas | 100% | 1700.75 | 328 / 328 | 100% | 30.15 | 178 / 178 |
skin | 100% | 3087.64 | 1809 / 1809 | 100% | 36.74 | 472 / 472 |
stomach | 100% | 2395.38 | 359 / 359 | 100% | 28.69 | 286 / 286 |
thymus | 100% | 2716.62 | 653 / 653 | 100% | 35.03 | 605 / 605 |
uterus | 100% | 2825.71 | 170 / 170 | 100% | 44.91 | 459 / 459 |
brain | 100% | 2173.16 | 2639 / 2642 | 100% | 33.99 | 705 / 705 |
intestine | 100% | 2824.83 | 966 / 966 | 100% | 32.60 | 526 / 527 |
bladder | 100% | 2457.86 | 21 / 21 | 100% | 39.79 | 503 / 504 |
prostate | 100% | 2863.81 | 245 / 245 | 100% | 38.07 | 501 / 502 |
liver | 100% | 1966.92 | 226 / 226 | 100% | 20.95 | 405 / 406 |
kidney | 100% | 2638.42 | 89 / 89 | 100% | 25.08 | 898 / 901 |
breast | 100% | 2475.15 | 459 / 459 | 100% | 34.16 | 1114 / 1118 |
adrenal gland | 100% | 2886.28 | 258 / 258 | 100% | 24.47 | 229 / 230 |
adipose | 100% | 2429.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 43.96 | 29 / 29 |
muscle | 100% | 2132.71 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3536.26 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 40.77 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 55.78 | 1 / 1 |
blood vessel | 100% | 2183.17 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 1732.99 | 859 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 21.85 | 79 / 80 |
peripheral blood | 97% | 2123.84 | 901 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0006986 | Biological process | response to unfolded protein |
GO_0085020 | Biological process | protein K6-linked ubiquitination |
GO_1903955 | Biological process | positive regulation of protein targeting to mitochondrion |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0036503 | Biological process | ERAD pathway |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005634 | Cellular component | nucleus |
GO_0061631 | Molecular function | ubiquitin conjugating enzyme activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | UBE2J2 |
Protein name | Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2) Ubiquitin conjugating enzyme E2 J2 E2 ubiquitin-conjugating enzyme (EC 2.3.2.23) |
Synonyms | NCUBE2 hCG_20420 |
Description | FUNCTION: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2 . . |
Accessions | A6NGS0 ENST00000435198.5 D6RD90 ENST00000400930.8 [Q8N2K1-3] D6RA15 B1AMF0 ENST00000450390.6 ENST00000488418.2 ENST00000360466.6 [Q8N2K1-1] ENST00000347370.6 ENST00000473215.5 ENST00000422076.5 ENST00000464036.5 ENST00000477894.5 ENST00000503294.5 ENST00000466752.5 D6REN4 ENST00000349431.11 [Q8N2K1-1] B1AMF1 D6RC43 ENST00000400929.6 ENST00000502382.1 D6R9H0 D6RB84 ENST00000509720.5 Q8N2K1 |