TMED5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	24 studies	25% ± 8%	Explore
classical monocyte	19 studies	26% ± 9%	Explore
non-classical monocyte	16 studies	26% ± 9%	Explore
natural killer cell	14 studies	20% ± 3%	Explore
fibroblast	12 studies	25% ± 9%	Explore
monocyte	11 studies	23% ± 4%	Explore
plasma cell	11 studies	37% ± 13%	Explore
plasmacytoid dendritic cell	11 studies	26% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	21% ± 4%	Explore
regulatory T cell	10 studies	19% ± 3%	Explore
gamma-delta T cell	10 studies	22% ± 7%	Explore
B cell	9 studies	19% ± 1%	Explore
plasmablast	8 studies	40% ± 23%	Explore
conventional dendritic cell	8 studies	27% ± 11%	Explore
endothelial cell	8 studies	21% ± 5%	Explore
mucosal invariant T cell	8 studies	21% ± 4%	Explore
myeloid cell	8 studies	27% ± 12%	Explore
epithelial cell	8 studies	31% ± 12%	Explore
alveolar macrophage	7 studies	32% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 2%	Explore
CD8-positive, alpha-beta T cell	7 studies	19% ± 3%	Explore
adipocyte	7 studies	29% ± 14%	Explore
memory B cell	7 studies	18% ± 4%	Explore
mature NK T cell	6 studies	17% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	20% ± 2%	Explore
dendritic cell	5 studies	33% ± 16%	Explore
basal cell	5 studies	22% ± 7%	Explore
naive B cell	5 studies	18% ± 3%	Explore
CD4-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
IgA plasma cell	4 studies	20% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	18% ± 3%	Explore
astrocyte	4 studies	25% ± 6%	Explore
oligodendrocyte precursor cell	4 studies	24% ± 6%	Explore
oligodendrocyte	4 studies	20% ± 4%	Explore
T cell	3 studies	19% ± 2%	Explore
mast cell	3 studies	22% ± 7%	Explore
type I pneumocyte	3 studies	23% ± 4%	Explore
pancreatic A cell	3 studies	27% ± 8%	Explore
leukocyte	3 studies	18% ± 3%	Explore
hematopoietic precursor cell	3 studies	25% ± 0%	Explore
mononuclear phagocyte	3 studies	24% ± 6%	Explore
tissue-resident macrophage	3 studies	21% ± 6%	Explore
ciliated cell	3 studies	30% ± 2%	Explore
intermediate monocyte	3 studies	39% ± 11%	Explore
innate lymphoid cell	3 studies	17% ± 1%	Explore
pericyte	3 studies	22% ± 5%	Explore
smooth muscle cell	3 studies	21% ± 2%	Explore
hepatocyte	3 studies	43% ± 20%	Explore
muscle cell	3 studies	19% ± 2%	Explore
GABAergic neuron	3 studies	30% ± 4%	Explore
glutamatergic neuron	3 studies	36% ± 5%	Explore
T follicular helper cell	3 studies	16% ± 1%	Explore
double negative thymocyte	3 studies	25% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	22% ± 5%	Explore
brain	5 studies	28% ± 3%	Explore
lung	4 studies	29% ± 9%	Explore
kidney	3 studies	19% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	4778.38	578 / 578	100%	30.47	1154 / 1155
esophagus	100%	2689.73	1443 / 1445	100%	27.49	183 / 183
liver	100%	5848.78	226 / 226	100%	34.85	404 / 406
breast	100%	3879.44	459 / 459	99%	27.78	1111 / 1118
kidney	100%	3930.97	89 / 89	99%	37.77	894 / 901
thymus	100%	3569.88	653 / 653	99%	26.82	600 / 605
prostate	100%	2707.29	244 / 245	99%	28.08	498 / 502
ovary	100%	2865.17	180 / 180	99%	16.94	424 / 430
uterus	100%	2421.87	170 / 170	98%	19.74	451 / 459
bladder	100%	3380.67	21 / 21	98%	26.00	495 / 504
brain	98%	1842.12	2595 / 2642	100%	29.71	704 / 705
stomach	100%	2656.13	359 / 359	98%	28.73	280 / 286
pancreas	99%	1909.45	326 / 328	98%	20.56	175 / 178
intestine	100%	3155.36	966 / 966	97%	25.63	511 / 527
adrenal gland	100%	5069.15	258 / 258	91%	15.26	210 / 230
skin	99%	2568.39	1792 / 1809	89%	22.15	421 / 472
lymph node	0%	0	0 / 0	100%	19.62	29 / 29
muscle	100%	4666.03	803 / 803	0%	0	0 / 0
spleen	100%	3449.18	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	15.65	45 / 45
ureter	0%	0	0 / 0	100%	8.95	1 / 1
blood vessel	100%	3476.17	1334 / 1335	0%	0	0 / 0
adipose	100%	5065.33	1203 / 1204	0%	0	0 / 0
heart	95%	2993.78	817 / 861	0%	0	0 / 0
peripheral blood	93%	3243.30	867 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	48%	5.03	38 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006886	Biological process	intracellular protein transport
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0090161	Biological process	Golgi ribbon formation
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0005801	Cellular component	cis-Golgi network
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005794	Cellular component	Golgi apparatus
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0070971	Cellular component	endoplasmic reticulum exit site
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0038024	Molecular function	cargo receptor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TMED5
Protein name	Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28) Transmembrane p24 trafficking protein 5 Transmembrane emp24 domain-containing protein 5
Synonyms	UNQ397/PRO733 CGI-100
Description	FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport. . FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport. . FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport. .
Accessions	Q9Y3A6 ENST00000370290.7 B1AKT3 Q49AG2 ENST00000479918.5 [Q9Y3A6-2] ENST00000370280.1 ENST00000370282.8 [Q9Y3A6-1] M0R072

TMED5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review