Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasma cell | 4 studies | 27% ± 12% | |
| epithelial cell | 4 studies | 27% ± 10% | |
| goblet cell | 4 studies | 21% ± 3% | |
| plasmablast | 3 studies | 42% ± 18% | |
| fibroblast | 3 studies | 21% ± 6% | |
| dendritic cell | 3 studies | 16% ± 1% |
Insufficient scRNA-seq data for expression of TMEM214 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 5180.07 | 1445 / 1445 | 100% | 101.07 | 183 / 183 |
| intestine | 100% | 6160.35 | 966 / 966 | 100% | 99.42 | 527 / 527 |
| ovary | 100% | 7034.49 | 180 / 180 | 100% | 78.98 | 430 / 430 |
| pancreas | 100% | 7975.02 | 328 / 328 | 100% | 82.80 | 178 / 178 |
| prostate | 100% | 8181.27 | 245 / 245 | 100% | 120.21 | 502 / 502 |
| skin | 100% | 6908.96 | 1809 / 1809 | 100% | 105.78 | 472 / 472 |
| stomach | 100% | 5543.39 | 359 / 359 | 100% | 100.94 | 286 / 286 |
| thymus | 100% | 8533.77 | 653 / 653 | 100% | 85.41 | 604 / 605 |
| uterus | 100% | 7745.38 | 170 / 170 | 100% | 80.91 | 458 / 459 |
| liver | 100% | 5416.64 | 226 / 226 | 100% | 61.94 | 405 / 406 |
| lung | 100% | 6854.51 | 578 / 578 | 100% | 90.54 | 1152 / 1155 |
| breast | 100% | 7685.47 | 459 / 459 | 99% | 101.01 | 1112 / 1118 |
| kidney | 100% | 5427.18 | 89 / 89 | 99% | 74.78 | 896 / 901 |
| bladder | 100% | 6388.90 | 21 / 21 | 99% | 88.17 | 500 / 504 |
| adrenal gland | 100% | 6795.73 | 258 / 258 | 99% | 62.63 | 227 / 230 |
| brain | 96% | 2378.03 | 2533 / 2642 | 100% | 41.07 | 703 / 705 |
| adipose | 100% | 7729.79 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 101.01 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 52.11 | 29 / 29 |
| spleen | 100% | 7380.23 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 63.00 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 34.98 | 1 / 1 |
| blood vessel | 100% | 7369.23 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 3980.02 | 856 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3175.86 | 793 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 3391.87 | 845 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005881 | Cellular component | cytoplasmic microtubule |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| Gene name | TMEM214 |
| Protein name | Transmembrane protein 214 TMEM214 protein |
| Synonyms | PP446 |
| Description | FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. . FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. . FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. . FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. . FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. . |
| Accessions | Q6NUQ4 B3LEU8 ENST00000434544.1 H7C0H8 ENST00000404032.7 [Q6NUQ4-2] H7C085 ENST00000425720.5 H7BZI0 H7C008 ENST00000444135.5 ENST00000435172.6 ENST00000321326.11 [Q6NUQ4-1] ENST00000238788.14 [Q6NUQ4-1] |
