TUNAR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TUNAR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TUNAR at tissue level.

III. Associated gene sets

GO_0048812Biological processneuron projection morphogenesis
GO_0051480Biological processregulation of cytosolic calcium ion concentration
GO_0045665Biological processnegative regulation of neuron differentiation
GO_0032469Biological processendoplasmic reticulum calcium ion homeostasis
GO_0035774Biological processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
GO_0005783Cellular componentendoplasmic reticulum
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0051117Molecular functionATPase binding

IV. Literature review

[source]
Gene nameTUNAR
Protein nameProtein TUNAR (pTUNAR) (Beta cell and neural cell-regulin) (BNLN) (TCL1 upstream neural differentiation-associated RNA)
HCG2038094, isoform CRA_b (TCL1 upstream neural differentiation-associated RNA)
SynonymshCG_2038094
DescriptionFUNCTION: In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (By similarity). Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (By similarity). In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion . .

AccessionsA0A1B0GTB2
ENST00000687554.1
ENST00000678517.1
ENST00000504119.1
A0A7I2V4K3
ENST00000503525.2
ENST00000554321.1