BFAR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_1903895Biological processnegative regulation of IRE1-mediated unfolded protein response
GO_0051865Biological processprotein autoubiquitination
GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0070534Biological processprotein K63-linked ubiquitination
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0043066Biological processnegative regulation of apoptotic process
GO_0000209Biological processprotein polyubiquitination
GO_0043161Biological processproteasome-mediated ubiquitin-dependent protein catabolic process
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0089720Molecular functioncaspase binding
GO_0030674Molecular functionprotein-macromolecule adaptor activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameBFAR
Protein nameBifunctional apoptosis regulator
Bifunctional apoptosis regulator (RING finger protein 47)
SynonymsRNF47
BAR
DescriptionFUNCTION: Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. .

AccessionsQ9NZS9
H3BRQ5
ENST00000566710.1
ENST00000562545.5
H3BPQ8
ENST00000563971.5
ENST00000562442.5
ENST00000634083.1
A0A087WXR3
ENST00000570219.1
ENST00000563313.5
ENST00000564078.1
ENST00000565478.1
ENST00000261658.7 [Q9NZS9-1]
H3BTG6
ENST00000632391.1
ENST00000634109.1
ENST00000631407.1
H3BMY8
H3BUB3
H3BMP2
H3BSU2
ENST00000633638.1
ENST00000632031.1
ENST00000631651.1
ENST00000632966.1
ENST00000619034.2 [Q9NZS9-1]