Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 21 studies | 29% ± 11% | |
macrophage | 19 studies | 24% ± 9% | |
non-classical monocyte | 15 studies | 23% ± 9% | |
microglial cell | 15 studies | 51% ± 20% | |
monocyte | 11 studies | 25% ± 10% | |
conventional dendritic cell | 8 studies | 22% ± 6% | |
endothelial cell | 7 studies | 21% ± 3% | |
myeloid cell | 7 studies | 30% ± 6% | |
dendritic cell | 6 studies | 27% ± 7% | |
endothelial cell of artery | 6 studies | 29% ± 7% | |
mononuclear phagocyte | 5 studies | 21% ± 6% | |
classical monocyte | 5 studies | 24% ± 7% | |
oligodendrocyte | 5 studies | 23% ± 4% | |
fibroblast | 4 studies | 20% ± 2% | |
alveolar macrophage | 4 studies | 24% ± 4% | |
hematopoietic precursor cell | 3 studies | 40% ± 25% | |
GABAergic neuron | 3 studies | 24% ± 9% | |
hematopoietic stem cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 26% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1287.68 | 1445 / 1445 | 99% | 24.57 | 181 / 183 |
intestine | 100% | 1122.45 | 965 / 966 | 94% | 18.98 | 496 / 527 |
lung | 99% | 1276.21 | 572 / 578 | 95% | 15.52 | 1096 / 1155 |
thymus | 100% | 7908.22 | 653 / 653 | 92% | 72.34 | 559 / 605 |
stomach | 96% | 783.14 | 344 / 359 | 95% | 18.55 | 272 / 286 |
ovary | 100% | 2124.34 | 180 / 180 | 90% | 9.72 | 387 / 430 |
adrenal gland | 98% | 1236.12 | 254 / 258 | 91% | 17.59 | 210 / 230 |
skin | 100% | 1535.43 | 1808 / 1809 | 89% | 20.75 | 421 / 472 |
uterus | 100% | 3285.29 | 170 / 170 | 87% | 13.35 | 400 / 459 |
breast | 100% | 2146.15 | 459 / 459 | 87% | 11.02 | 972 / 1118 |
bladder | 100% | 1525.00 | 21 / 21 | 84% | 13.94 | 424 / 504 |
kidney | 98% | 940.71 | 87 / 89 | 84% | 12.86 | 759 / 901 |
prostate | 99% | 1316.46 | 242 / 245 | 72% | 6.06 | 359 / 502 |
pancreas | 56% | 277.40 | 183 / 328 | 93% | 18.72 | 166 / 178 |
brain | 58% | 690.92 | 1544 / 2642 | 82% | 11.18 | 581 / 705 |
adipose | 100% | 2034.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1714.17 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 96% | 1283.60 | 1287 / 1335 | 0% | 0 | 0 / 0 |
heart | 94% | 770.17 | 813 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 12.32 | 42 / 45 |
peripheral blood | 80% | 3503.01 | 747 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 52% | 3.86 | 15 / 29 |
muscle | 37% | 185.17 | 295 / 803 | 0% | 0 | 0 / 0 |
liver | 3% | 12.85 | 7 / 226 | 27% | 2.67 | 109 / 406 |
eye | 0% | 0 | 0 / 0 | 14% | 0.77 | 11 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0061024 | Biological process | membrane organization |
GO_0036151 | Biological process | phosphatidylcholine acyl-chain remodeling |
GO_0006663 | Biological process | platelet activating factor biosynthetic process |
GO_0005795 | Cellular component | Golgi stack |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005886 | Cellular component | plasma membrane |
GO_0005811 | Cellular component | lipid droplet |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0047192 | Molecular function | 1-alkylglycerophosphocholine O-acetyltransferase activity |
GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0047159 | Molecular function | plasmalogen synthase activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0047184 | Molecular function | 1-acylglycerophosphocholine O-acyltransferase activity |
GO_0042171 | Molecular function | lysophosphatidic acid acyltransferase activity |
Gene name | LPCAT2 |
Protein name | Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) Lysophosphatidylcholine acyltransferase 2 |
Synonyms | AYTL1 AGPAT11 |
Description | FUNCTION: Exhibits both acyltransferase and acetyltransferase activities . Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) . Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) . Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor (By similarity). Under resting conditions, acyltransferase activity is preferred (By similarity). Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases (By similarity). Involved in the regulation of lipid droplet number and size . . |
Accessions | ENST00000564084.1 Q7L5N7 H3BU68 ENST00000262134.10 [Q7L5N7-1] |