I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| secretory cell | 4 studies | 25% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| secretory cell | 4 studies | 25% ± 10% |
Insufficient scRNA-seq data for expression of DUOXA2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 995.07 | 651 / 653 | 80% | 43.32 | 484 / 605 |
| stomach | 77% | 932.72 | 276 / 359 | 57% | 29.53 | 163 / 286 |
| esophagus | 44% | 198.62 | 640 / 1445 | 64% | 26.35 | 117 / 183 |
| pancreas | 15% | 34.56 | 48 / 328 | 80% | 67.49 | 143 / 178 |
| bladder | 57% | 96.33 | 12 / 21 | 38% | 19.08 | 189 / 504 |
| lung | 73% | 55.95 | 420 / 578 | 17% | 5.17 | 198 / 1155 |
| intestine | 21% | 100.01 | 203 / 966 | 68% | 39.12 | 358 / 527 |
| prostate | 75% | 176.54 | 183 / 245 | 2% | 0.18 | 10 / 502 |
| skin | 70% | 77.66 | 1267 / 1809 | 0% | 0.01 | 1 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 47% | 11.83 | 21 / 45 |
| adrenal gland | 37% | 21.86 | 95 / 258 | 4% | 0.83 | 9 / 230 |
| uterus | 5% | 4.16 | 8 / 170 | 35% | 13.68 | 161 / 459 |
| liver | 13% | 13.94 | 30 / 226 | 14% | 8.43 | 57 / 406 |
| kidney | 12% | 4.54 | 11 / 89 | 0% | 0.02 | 3 / 901 |
| ovary | 7% | 3.43 | 13 / 180 | 1% | 0.06 | 3 / 430 |
| breast | 8% | 9.20 | 35 / 459 | 0% | 0.02 | 3 / 1118 |
| heart | 4% | 1.42 | 38 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 4% | 1.96 | 54 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 3% | 3.32 | 42 / 1204 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.10 | 5 / 2642 | 0% | 0.04 | 2 / 705 |
| muscle | 0% | 0.06 | 1 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.47 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_2000609 | Biological process | regulation of thyroid hormone generation |
| GO_0015031 | Biological process | protein transport |
| GO_0008104 | Biological process | protein localization |
| GO_2000147 | Biological process | positive regulation of cell motility |
| GO_0042743 | Biological process | hydrogen peroxide metabolic process |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0010729 | Biological process | positive regulation of hydrogen peroxide biosynthetic process |
| GO_0051604 | Biological process | protein maturation |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0045177 | Cellular component | apical part of cell |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0031252 | Cellular component | cell leading edge |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DUOXA2 |
| Protein name | Dual oxidase maturation factor 2 (Dual oxidase activator 2) |
| Synonyms | |
| Description | FUNCTION: Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis. . |
| Accessions | Q1HG44 ENST00000323030.6 [Q1HG44-1] ENST00000491993.2 [Q1HG44-2] |
