MAN1A2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	23 studies	29% ± 11%	Explore
natural killer cell	14 studies	20% ± 4%	Explore
regulatory T cell	13 studies	21% ± 5%	Explore
fibroblast	13 studies	23% ± 6%	Explore
ciliated cell	12 studies	26% ± 9%	Explore
glutamatergic neuron	12 studies	51% ± 27%	Explore
oligodendrocyte precursor cell	12 studies	36% ± 13%	Explore
GABAergic neuron	11 studies	47% ± 28%	Explore
CD8-positive, alpha-beta T cell	11 studies	19% ± 3%	Explore
astrocyte	11 studies	29% ± 14%	Explore
microglial cell	10 studies	24% ± 7%	Explore
oligodendrocyte	10 studies	34% ± 10%	Explore
plasma cell	9 studies	30% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	24% ± 10%	Explore
epithelial cell	9 studies	37% ± 18%	Explore
basal cell	8 studies	28% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	18% ± 2%	Explore
macrophage	8 studies	28% ± 8%	Explore
adipocyte	8 studies	33% ± 8%	Explore
T cell	8 studies	23% ± 8%	Explore
plasmacytoid dendritic cell	8 studies	20% ± 5%	Explore
B cell	7 studies	21% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	23% ± 11%	Explore
neuron	7 studies	37% ± 15%	Explore
smooth muscle cell	7 studies	21% ± 3%	Explore
endothelial cell of lymphatic vessel	6 studies	27% ± 8%	Explore
respiratory goblet cell	6 studies	29% ± 10%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 2%	Explore
classical monocyte	6 studies	22% ± 8%	Explore
interneuron	6 studies	53% ± 26%	Explore
mucosal invariant T cell	6 studies	16% ± 1%	Explore
myofibroblast cell	6 studies	20% ± 4%	Explore
club cell	6 studies	27% ± 8%	Explore
type II pneumocyte	6 studies	20% ± 4%	Explore
pericyte	6 studies	21% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	24% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
myeloid cell	5 studies	21% ± 4%	Explore
retina horizontal cell	5 studies	25% ± 7%	Explore
retinal cone cell	5 studies	28% ± 5%	Explore
retinal rod cell	5 studies	18% ± 3%	Explore
cardiac muscle cell	5 studies	24% ± 5%	Explore
type I pneumocyte	5 studies	22% ± 5%	Explore
secretory cell	4 studies	24% ± 5%	Explore
hematopoietic precursor cell	4 studies	25% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	25% ± 11%	Explore
granule cell	4 studies	30% ± 10%	Explore
amacrine cell	4 studies	25% ± 9%	Explore
retinal pigment epithelial cell	4 studies	31% ± 18%	Explore
lymphocyte	4 studies	33% ± 9%	Explore
dendritic cell	4 studies	30% ± 14%	Explore
monocyte	4 studies	20% ± 4%	Explore
goblet cell	4 studies	34% ± 22%	Explore
pancreatic A cell	3 studies	34% ± 19%	Explore
mature NK T cell	3 studies	22% ± 7%	Explore
plasmablast	3 studies	43% ± 14%	Explore
GABAergic interneuron	3 studies	55% ± 3%	Explore
retinal ganglion cell	3 studies	27% ± 6%	Explore
extravillous trophoblast	3 studies	37% ± 8%	Explore
immature B cell	3 studies	31% ± 8%	Explore
pro-B cell	3 studies	29% ± 7%	Explore
retinal bipolar neuron	3 studies	25% ± 6%	Explore
Mueller cell	3 studies	20% ± 2%	Explore
GABAergic amacrine cell	3 studies	24% ± 8%	Explore
OFF-bipolar cell	3 studies	26% ± 5%	Explore
ON-bipolar cell	3 studies	25% ± 4%	Explore
glycinergic amacrine cell	3 studies	24% ± 2%	Explore
rod bipolar cell	3 studies	25% ± 3%	Explore
endothelial cell of vascular tree	3 studies	23% ± 10%	Explore
hepatocyte	3 studies	47% ± 16%	Explore
abnormal cell	3 studies	26% ± 10%	Explore
connective tissue cell	3 studies	22% ± 5%	Explore
enteroendocrine cell	3 studies	20% ± 5%	Explore
gamma-delta T cell	3 studies	25% ± 10%	Explore
hematopoietic stem cell	3 studies	25% ± 8%	Explore
mast cell	3 studies	23% ± 4%	Explore
naive B cell	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	40% ± 22%	Explore
eye	8 studies	23% ± 10%	Explore
lung	6 studies	23% ± 5%	Explore
peripheral blood	4 studies	26% ± 7%	Explore
liver	4 studies	26% ± 11%	Explore
adipose	4 studies	21% ± 4%	Explore
pancreas	3 studies	38% ± 15%	Explore
placenta	3 studies	22% ± 3%	Explore
heart	3 studies	21% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3191.85	1445 / 1445	100%	32.93	183 / 183
ovary	100%	2906.94	180 / 180	100%	17.73	430 / 430
brain	100%	2760.06	2641 / 2642	100%	23.09	705 / 705
breast	100%	2918.83	459 / 459	100%	30.55	1117 / 1118
lung	100%	2631.18	577 / 578	100%	23.84	1155 / 1155
prostate	100%	3015.11	245 / 245	100%	23.37	501 / 502
bladder	100%	3592.90	21 / 21	99%	19.90	500 / 504
thymus	100%	3739.66	653 / 653	99%	28.49	600 / 605
pancreas	100%	3870.10	328 / 328	99%	20.45	176 / 178
uterus	100%	4157.15	170 / 170	99%	20.42	453 / 459
stomach	100%	2562.33	359 / 359	98%	21.50	279 / 286
intestine	100%	3227.76	966 / 966	98%	17.36	514 / 527
kidney	100%	1974.81	89 / 89	97%	19.94	878 / 901
liver	100%	2369.65	226 / 226	96%	14.20	391 / 406
adrenal gland	100%	2716.98	258 / 258	94%	15.11	216 / 230
skin	100%	3120.49	1806 / 1809	93%	20.11	437 / 472
blood vessel	100%	3842.59	1335 / 1335	0%	0	0 / 0
spleen	100%	2422.19	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	21.85	45 / 45
ureter	0%	0	0 / 0	100%	15.76	1 / 1
adipose	100%	3159.66	1203 / 1204	0%	0	0 / 0
muscle	100%	1920.94	801 / 803	0%	0	0 / 0
heart	97%	1876.77	837 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	10.75	26 / 29
peripheral blood	65%	1146.16	603 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	50%	4.25	40 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0005975	Biological process	carbohydrate metabolic process
GO_1904382	Biological process	mannose trimming involved in glycoprotein ERAD pathway
GO_0048286	Biological process	lung alveolus development
GO_0006491	Biological process	N-glycan processing
GO_0006486	Biological process	protein glycosylation
GO_0007585	Biological process	respiratory gaseous exchange by respiratory system
GO_0000139	Cellular component	Golgi membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005794	Cellular component	Golgi apparatus
GO_0016020	Cellular component	membrane
GO_0004571	Molecular function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO_0005509	Molecular function	calcium ion binding

IV. Literature review

[source]

Gene name	MAN1A2
Protein name	alpha-1,2-Mannosidase (EC 3.2.1.-) Mannosidase alpha class 1A member 2 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)
Synonyms	MAN1B
Description	FUNCTION: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Accessions	H0Y543 ENST00000421535.5 O60476 ENST00000356554.7 ENST00000449370.6 ENST00000422329.1 H0Y7H1 Q5T9E3

MAN1A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review