IER3IP1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	17 studies	28% ± 13%	Explore
natural killer cell	15 studies	22% ± 7%	Explore
fibroblast	14 studies	28% ± 9%	Explore
CD8-positive, alpha-beta T cell	10 studies	22% ± 5%	Explore
pericyte	10 studies	25% ± 9%	Explore
capillary endothelial cell	9 studies	20% ± 4%	Explore
plasma cell	8 studies	32% ± 14%	Explore
plasmacytoid dendritic cell	8 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	7 studies	22% ± 5%	Explore
epithelial cell of proximal tubule	7 studies	30% ± 9%	Explore
connective tissue cell	7 studies	29% ± 12%	Explore
endothelial cell of artery	7 studies	23% ± 6%	Explore
epithelial cell	7 studies	44% ± 21%	Explore
non-classical monocyte	6 studies	23% ± 5%	Explore
macrophage	6 studies	24% ± 6%	Explore
smooth muscle cell	6 studies	22% ± 5%	Explore
basal cell	6 studies	34% ± 18%	Explore
plasmablast	5 studies	49% ± 20%	Explore
classical monocyte	5 studies	22% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	22% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	18% ± 3%	Explore
myofibroblast cell	5 studies	24% ± 8%	Explore
mature NK T cell	5 studies	19% ± 2%	Explore
T cell	5 studies	18% ± 3%	Explore
mucosal invariant T cell	5 studies	17% ± 1%	Explore
ciliated cell	5 studies	40% ± 13%	Explore
endothelial cell of lymphatic vessel	5 studies	29% ± 6%	Explore
gamma-delta T cell	5 studies	22% ± 9%	Explore
conventional dendritic cell	4 studies	30% ± 7%	Explore
kidney loop of Henle epithelial cell	4 studies	21% ± 2%	Explore
vein endothelial cell	4 studies	20% ± 3%	Explore
abnormal cell	4 studies	23% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	19% ± 2%	Explore
endothelial cell of vascular tree	4 studies	22% ± 6%	Explore
B cell	4 studies	21% ± 9%	Explore
type II pneumocyte	4 studies	30% ± 19%	Explore
dendritic cell	4 studies	30% ± 12%	Explore
regulatory T cell	4 studies	21% ± 4%	Explore
secretory cell	4 studies	26% ± 13%	Explore
pancreatic A cell	3 studies	54% ± 9%	Explore
pancreatic D cell	3 studies	48% ± 10%	Explore
type B pancreatic cell	3 studies	52% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	21% ± 3%	Explore
hematopoietic precursor cell	3 studies	24% ± 2%	Explore
glomerular endothelial cell	3 studies	25% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	29% ± 4%	Explore
renal alpha-intercalated cell	3 studies	28% ± 7%	Explore
retinal cone cell	3 studies	53% ± 21%	Explore
monocyte	3 studies	20% ± 4%	Explore
neuron	3 studies	30% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
goblet cell	3 studies	31% ± 12%	Explore
intestinal crypt stem cell	3 studies	21% ± 4%	Explore
T-helper 17 cell	3 studies	22% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	20% ± 2%	Explore
lung	8 studies	29% ± 11%	Explore
kidney	6 studies	21% ± 5%	Explore
intestine	4 studies	27% ± 16%	Explore
pancreas	3 studies	47% ± 15%	Explore
brain	3 studies	28% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1507.63	1445 / 1445	100%	24.42	183 / 183
kidney	100%	2789.92	89 / 89	100%	25.75	901 / 901
lung	100%	2176.59	578 / 578	100%	29.62	1155 / 1155
ovary	100%	1644.95	180 / 180	100%	21.54	430 / 430
uterus	100%	1671.76	170 / 170	100%	32.61	459 / 459
prostate	100%	1798.53	245 / 245	100%	33.72	501 / 502
liver	100%	1696.06	226 / 226	100%	20.34	405 / 406
thymus	100%	1884.59	653 / 653	100%	29.41	603 / 605
adrenal gland	100%	2124.65	258 / 258	100%	45.60	229 / 230
brain	100%	1302.38	2630 / 2642	100%	17.71	705 / 705
breast	100%	2030.26	459 / 459	99%	36.90	1112 / 1118
skin	100%	2479.18	1808 / 1809	99%	26.65	467 / 472
pancreas	100%	1208.75	328 / 328	99%	19.06	176 / 178
bladder	100%	1730.71	21 / 21	98%	26.30	496 / 504
intestine	100%	1672.98	966 / 966	96%	18.43	508 / 527
stomach	100%	1485.07	359 / 359	96%	20.18	275 / 286
adipose	100%	2094.89	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	22.09	29 / 29
muscle	100%	2243.63	803 / 803	0%	0	0 / 0
spleen	100%	1632.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	28.78	45 / 45
ureter	0%	0	0 / 0	100%	10.53	1 / 1
blood vessel	100%	1749.39	1332 / 1335	0%	0	0 / 0
heart	99%	1536.25	856 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	16.61	75 / 80
peripheral blood	58%	773.55	540 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0