Name | Number of supported studies | Average coverage | |
---|---|---|---|
plasmacytoid dendritic cell | 7 studies | 25% ± 8% | |
classical monocyte | 6 studies | 22% ± 7% | |
epithelial cell | 6 studies | 39% ± 16% | |
CD8-positive, alpha-beta T cell | 6 studies | 21% ± 4% | |
natural killer cell | 6 studies | 19% ± 4% | |
CD4-positive, alpha-beta T cell | 5 studies | 26% ± 5% | |
plasmablast | 4 studies | 40% ± 20% | |
conventional dendritic cell | 4 studies | 26% ± 8% | |
goblet cell | 4 studies | 25% ± 10% | |
basal cell | 4 studies | 32% ± 16% | |
regulatory T cell | 4 studies | 20% ± 3% | |
hematopoietic precursor cell | 3 studies | 29% ± 4% | |
non-classical monocyte | 3 studies | 32% ± 5% | |
transit amplifying cell | 3 studies | 28% ± 3% | |
type I pneumocyte | 3 studies | 28% ± 8% | |
ciliated cell | 3 studies | 27% ± 2% | |
macrophage | 3 studies | 24% ± 4% | |
dendritic cell | 3 studies | 36% ± 5% | |
enterocyte | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
intestine | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 1665.49 | 328 / 328 | 100% | 53.34 | 178 / 178 |
prostate | 100% | 1260.89 | 245 / 245 | 99% | 60.52 | 498 / 502 |
intestine | 100% | 1360.55 | 963 / 966 | 99% | 85.83 | 524 / 527 |
liver | 100% | 1224.03 | 225 / 226 | 100% | 41.19 | 404 / 406 |
esophagus | 99% | 1407.67 | 1431 / 1445 | 100% | 69.02 | 183 / 183 |
stomach | 100% | 1640.05 | 358 / 359 | 99% | 76.19 | 284 / 286 |
thymus | 100% | 803.94 | 652 / 653 | 99% | 29.71 | 599 / 605 |
bladder | 100% | 818.81 | 21 / 21 | 98% | 77.54 | 495 / 504 |
kidney | 100% | 1252.08 | 89 / 89 | 98% | 36.77 | 884 / 901 |
breast | 100% | 906.32 | 458 / 459 | 98% | 48.71 | 1096 / 1118 |
skin | 100% | 1661.30 | 1802 / 1809 | 98% | 43.30 | 461 / 472 |
adrenal gland | 100% | 1048.44 | 257 / 258 | 96% | 30.70 | 221 / 230 |
lung | 97% | 1143.87 | 560 / 578 | 98% | 56.99 | 1134 / 1155 |
uterus | 96% | 519.11 | 163 / 170 | 99% | 73.76 | 455 / 459 |
ovary | 76% | 293.14 | 137 / 180 | 100% | 71.48 | 430 / 430 |
brain | 66% | 234.64 | 1737 / 2642 | 54% | 11.99 | 381 / 705 |
eye | 0% | 0 | 0 / 0 | 100% | 39.40 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 75.82 | 29 / 29 |
spleen | 100% | 1387.81 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 81.72 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 55.49 | 1 / 1 |
adipose | 99% | 832.40 | 1195 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2369.36 | 912 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 652.77 | 1296 / 1335 | 0% | 0 | 0 / 0 |
heart | 81% | 353.56 | 696 / 861 | 0% | 0 | 0 / 0 |
muscle | 76% | 375.57 | 614 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0018345 | Biological process | protein palmitoylation |
GO_0018230 | Biological process | peptidyl-L-cysteine S-palmitoylation |
GO_0032230 | Biological process | positive regulation of synaptic transmission, GABAergic |
GO_0006612 | Biological process | protein targeting to membrane |
GO_0097116 | Biological process | gephyrin clustering involved in postsynaptic density assembly |
GO_1900226 | Biological process | negative regulation of NLRP3 inflammasome complex assembly |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0016409 | Molecular function | palmitoyltransferase activity |
GO_0019706 | Molecular function | protein-cysteine S-palmitoyltransferase activity |
Gene name | ZDHHC12 |
Protein name | Palmitoyltransferase (EC 2.3.1.225) Palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 12) (DHHC-12) (Zinc finger DHHC domain-containing protein 12) (Zinc finger protein 400) |
Synonyms | ZNF400 PSEC0008 |
Description | FUNCTION: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates . Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering (By similarity). Thereby, indirectly regulates GABAergic synaptic transmission (By similarity). Acts as an inhibitor of the NLRP3 inflammasome by mediating palmitoylation of NLRP3, thereby promoting NLRP3 degradation by the chaperone-mediated autophagy (CMA) process . . |
Accessions | Q5T266 ENST00000452105.5 ENST00000372663.9 [Q96GR4-1] Q5T269 ENST00000406904.2 ENST00000372667.9 Q96GR4 X6RBN4 |