Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type II pneumocyte | 9 studies | 28% ± 11% | |
| endothelial cell | 7 studies | 22% ± 8% | |
| type I pneumocyte | 7 studies | 25% ± 7% | |
| epithelial cell | 5 studies | 36% ± 17% | |
| goblet cell | 4 studies | 17% ± 1% | |
| transit amplifying cell | 3 studies | 39% ± 28% |
Insufficient scRNA-seq data for expression of ITPR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 98% | 7248.80 | 1422 / 1445 | 100% | 147.74 | 183 / 183 |
| stomach | 99% | 11360.27 | 355 / 359 | 99% | 86.70 | 282 / 286 |
| lung | 100% | 16560.05 | 577 / 578 | 97% | 71.88 | 1115 / 1155 |
| intestine | 97% | 11704.78 | 940 / 966 | 98% | 81.48 | 519 / 527 |
| thymus | 100% | 29471.19 | 652 / 653 | 93% | 86.08 | 565 / 605 |
| skin | 100% | 23052.16 | 1809 / 1809 | 91% | 59.66 | 430 / 472 |
| breast | 99% | 8120.20 | 456 / 459 | 90% | 34.28 | 1001 / 1118 |
| ovary | 98% | 6603.46 | 177 / 180 | 88% | 42.73 | 379 / 430 |
| uterus | 98% | 5882.83 | 167 / 170 | 81% | 46.86 | 374 / 459 |
| bladder | 95% | 6350.71 | 20 / 21 | 84% | 40.46 | 422 / 504 |
| prostate | 98% | 7982.35 | 240 / 245 | 70% | 20.88 | 352 / 502 |
| kidney | 91% | 7265.62 | 81 / 89 | 75% | 29.46 | 678 / 901 |
| pancreas | 69% | 3153.77 | 226 / 328 | 92% | 56.46 | 163 / 178 |
| adrenal gland | 97% | 5903.22 | 249 / 258 | 14% | 4.00 | 33 / 230 |
| spleen | 100% | 21223.92 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.06 | 1 / 1 |
| adipose | 99% | 8316.44 | 1188 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 73.12 | 42 / 45 |
| heart | 86% | 3952.83 | 737 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 65% | 13.87 | 52 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 14.83 | 16 / 29 |
| blood vessel | 55% | 2561.56 | 731 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 40% | 3012.06 | 376 / 929 | 0% | 0 | 0 / 0 |
| liver | 1% | 54.17 | 3 / 226 | 17% | 5.80 | 69 / 406 |
| brain | 10% | 367.18 | 269 / 2642 | 5% | 0.85 | 35 / 705 |
| muscle | 10% | 334.77 | 80 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0055074 | Biological process | calcium ion homeostasis |
| GO_0050917 | Biological process | sensory perception of umami taste |
| GO_0019722 | Biological process | calcium-mediated signaling |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0060291 | Biological process | long-term synaptic potentiation |
| GO_0050909 | Biological process | sensory perception of taste |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0050913 | Biological process | sensory perception of bitter taste |
| GO_0007613 | Biological process | memory |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0050916 | Biological process | sensory perception of sweet taste |
| GO_0051289 | Biological process | protein homotetramerization |
| GO_0005903 | Cellular component | brush border |
| GO_0005730 | Cellular component | nucleolus |
| GO_0030667 | Cellular component | secretory granule membrane |
| GO_0043235 | Cellular component | receptor complex |
| GO_0043209 | Cellular component | myelin sheath |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0098554 | Cellular component | cytoplasmic side of endoplasmic reticulum membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005640 | Cellular component | nuclear outer membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016529 | Cellular component | sarcoplasmic reticulum |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045177 | Cellular component | apical part of cell |
| GO_0031095 | Cellular component | platelet dense tubular network membrane |
| GO_0000822 | Molecular function | inositol hexakisphosphate binding |
| GO_0035091 | Molecular function | phosphatidylinositol binding |
| GO_0070679 | Molecular function | inositol 1,4,5 trisphosphate binding |
| GO_0043533 | Molecular function | inositol 1,3,4,5 tetrakisphosphate binding |
| GO_0005220 | Molecular function | inositol 1,4,5-trisphosphate-gated calcium channel activity |
| GO_0015278 | Molecular function | intracellularly gated calcium channel activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ITPR3 |
| Protein name | Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) |
| Synonyms | |
| Description | FUNCTION: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium (By similarity). Involved in cellular calcium ion homeostasis . . FUNCTION: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. . |
| Accessions | ENST00000605930.3 A6H8K3 ENST00000374316.9 Q14573 |
