POMT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030198Biological processextracellular matrix organization
GO_1904100Biological processpositive regulation of protein O-linked glycosylation
GO_0006493Biological processprotein O-linked glycosylation
GO_0035269Biological processprotein O-linked mannosylation
GO_0005783Cellular componentendoplasmic reticulum
GO_0001669Cellular componentacrosomal vesicle
GO_0016529Cellular componentsarcoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004169Molecular functiondolichyl-phosphate-mannose-protein mannosyltransferase activity
GO_0046872Molecular functionmetal ion binding
GO_0000030Molecular functionmannosyltransferase activity

IV. Literature review

[source]
Gene namePOMT1
Protein nameProtein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1)
Protein O-mannosyltransferase 1
Protein O-mannosyltransferase 1 (Truncated O-mannosyl-transferase 1 variant SV3DEL (EC 2.4.1.109))
Dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109)
dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109)
SynonymshCG_29235
DescriptionFUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient . Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins . .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

FUNCTION: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. .

AccessionsENST00000682639.1
A0A7I2YQK3
A0A7I2V5P7
A0A7I2V4L4
A0A804HKU5
Q5JT02
ENST00000677029.1
Q5JT07
A0A7I2V4U3
A0A7I2V3H8
ENST00000678833.1
ENST00000677099.1
A0A7I2V2T7
ENST00000678303.1
ENST00000448212.5
Q5JT05
ENST00000678739.1
A0A7I2V505
ENST00000677167.1
ENST00000678264.2
ENST00000677944.1
A0A804HI97
ENST00000679076.1
A0A7I2V3L5
ENST00000676803.1
ENST00000677729.1
ENST00000372220.5
ENST00000679023.1 [Q9Y6A1-3]
ENST00000415075.6
ENST00000679111.1
ENST00000677293.1
A0A804HHZ8
ENST00000683229.1
ENST00000677853.1
Q5JT03
Q9Y6A1
A0A7I2V356
A0A7I2V524
ENST00000678548.1
A0A7I2V5S7
A0A7I2V5V4
ENST00000430619.2
A0A7I2V2K0
ENST00000418774.6
ENST00000683231.1
ENST00000341012.13 [Q9Y6A1-3]
ENST00000678366.1
A0A7I2V2G9
ENST00000677028.1
A0A804HKS2
ENST00000678942.2
ENST00000677295.2
ENST00000683615.1
ENST00000677216.1 [Q9Y6A1-4]
A0A7I2V568
ENST00000679221.1
A0A7I2V5W1
ENST00000676835.1
B4DTW4
ENST00000678733.1
Q5JT04
A0A7I2V445
ENST00000676915.1
ENST00000441334.5
ENST00000678785.1
ENST00000684399.1
ENST00000679189.1 [Q9Y6A1-4]
A0A7I2V5X3
ENST00000423007.6
ENST00000677626.1
ENST00000683134.1
A0A7I2V4U0
B4DWD8
ENST00000402686.8 [Q9Y6A1-2]
Q5JSZ6
ENST00000676640.1 [Q9Y6A1-2]
A0A804HIE5
ENST00000682539.1
ENST00000372228.9 [Q9Y6A1-1]
A0A1V1FTP4