RPS6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	52 studies	89% ± 22%	Explore
macrophage	46 studies	78% ± 25%	Explore
natural killer cell	45 studies	89% ± 18%	Explore
endothelial cell	45 studies	75% ± 27%	Explore
fibroblast	42 studies	81% ± 27%	Explore
T cell	41 studies	85% ± 22%	Explore
CD8-positive, alpha-beta T cell	41 studies	88% ± 19%	Explore
pericyte	37 studies	79% ± 27%	Explore
CD4-positive, alpha-beta T cell	36 studies	93% ± 14%	Explore
conventional dendritic cell	32 studies	94% ± 12%	Explore
plasmacytoid dendritic cell	31 studies	96% ± 6%	Explore
smooth muscle cell	30 studies	81% ± 28%	Explore
dendritic cell	28 studies	90% ± 17%	Explore
endothelial cell of lymphatic vessel	28 studies	79% ± 28%	Explore
regulatory T cell	28 studies	93% ± 15%	Explore
plasma cell	27 studies	85% ± 22%	Explore
monocyte	26 studies	80% ± 23%	Explore
classical monocyte	26 studies	88% ± 12%	Explore
epithelial cell	26 studies	83% ± 24%	Explore
mast cell	25 studies	80% ± 23%	Explore
non-classical monocyte	25 studies	91% ± 10%	Explore
mature NK T cell	24 studies	88% ± 19%	Explore
basal cell	22 studies	89% ± 19%	Explore
gamma-delta T cell	21 studies	94% ± 9%	Explore
memory B cell	21 studies	98% ± 4%	Explore
connective tissue cell	20 studies	87% ± 21%	Explore
naive B cell	18 studies	97% ± 6%	Explore
ciliated cell	17 studies	81% ± 19%	Explore
mucosal invariant T cell	17 studies	95% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	96% ± 11%	Explore
capillary endothelial cell	17 studies	74% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	90% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	90% ± 15%	Explore
endothelial cell of artery	16 studies	83% ± 13%	Explore
microglial cell	15 studies	53% ± 31%	Explore
vein endothelial cell	15 studies	85% ± 19%	Explore
innate lymphoid cell	14 studies	92% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	99% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	14 studies	90% ± 19%	Explore
erythrocyte	14 studies	64% ± 25%	Explore
myofibroblast cell	14 studies	90% ± 18%	Explore
myeloid cell	14 studies	83% ± 22%	Explore
neutrophil	13 studies	63% ± 26%	Explore
mesothelial cell	13 studies	80% ± 24%	Explore
endothelial cell of vascular tree	13 studies	82% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	86% ± 20%	Explore
plasmablast	12 studies	94% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	94% ± 8%	Explore
secretory cell	12 studies	93% ± 10%	Explore
astrocyte	12 studies	37% ± 20%	Explore
progenitor cell	11 studies	87% ± 24%	Explore
leukocyte	11 studies	83% ± 23%	Explore
goblet cell	11 studies	88% ± 12%	Explore
type II pneumocyte	10 studies	79% ± 28%	Explore
T follicular helper cell	10 studies	98% ± 2%	Explore
IgG plasma cell	10 studies	87% ± 14%	Explore
type I pneumocyte	9 studies	73% ± 23%	Explore
club cell	9 studies	81% ± 27%	Explore
neuron	9 studies	67% ± 22%	Explore
IgA plasma cell	9 studies	84% ± 18%	Explore
hematopoietic stem cell	9 studies	91% ± 24%	Explore
platelet	8 studies	56% ± 26%	Explore
abnormal cell	8 studies	82% ± 25%	Explore
enterocyte	8 studies	77% ± 17%	Explore
respiratory goblet cell	7 studies	82% ± 12%	Explore
mononuclear phagocyte	7 studies	85% ± 22%	Explore
glutamatergic neuron	7 studies	36% ± 16%	Explore
oligodendrocyte	7 studies	34% ± 12%	Explore
epithelial cell of proximal tubule	7 studies	85% ± 17%	Explore
oligodendrocyte precursor cell	7 studies	39% ± 27%	Explore
enteroendocrine cell	7 studies	87% ± 17%	Explore
transit amplifying cell	7 studies	82% ± 26%	Explore
retinal rod cell	7 studies	54% ± 27%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	97% ± 4%	Explore
alveolar macrophage	6 studies	81% ± 23%	Explore
CD4-positive helper T cell	6 studies	85% ± 24%	Explore
hematopoietic precursor cell	6 studies	82% ± 30%	Explore
ionocyte	6 studies	85% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	87% ± 18%	Explore
renal alpha-intercalated cell	6 studies	99% ± 1%	Explore
erythroblast	6 studies	81% ± 17%	Explore
intestinal crypt stem cell	6 studies	79% ± 29%	Explore
amacrine cell	6 studies	43% ± 21%	Explore
retinal ganglion cell	6 studies	55% ± 26%	Explore
precursor B cell	6 studies	98% ± 2%	Explore
brush cell	6 studies	86% ± 16%	Explore
glial cell	6 studies	71% ± 26%	Explore
immature B cell	6 studies	99% ± 1%	Explore
melanocyte	6 studies	65% ± 31%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	98% ± 4%	Explore
CD4-positive, alpha-beta cytotoxic T cell	5 studies	85% ± 17%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	96% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	92% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	97% ± 3%	Explore
megakaryocyte	5 studies	76% ± 20%	Explore
OFF-bipolar cell	5 studies	61% ± 27%	Explore
ON-bipolar cell	5 studies	62% ± 27%	Explore
retinal cone cell	5 studies	64% ± 27%	Explore
lymphocyte	5 studies	85% ± 27%	Explore
T-helper 17 cell	5 studies	99% ± 1%	Explore
group 3 innate lymphoid cell	5 studies	97% ± 2%	Explore
Mueller cell	5 studies	63% ± 21%	Explore
double negative thymocyte	5 studies	98% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	98% ± 3%	Explore
granulocyte	5 studies	94% ± 7%	Explore
GABAergic neuron	5 studies	35% ± 9%	Explore
intermediate monocyte	5 studies	86% ± 11%	Explore
interneuron	5 studies	46% ± 25%	Explore
deuterosomal cell	4 studies	83% ± 13%	Explore
duct epithelial cell	4 studies	97% ± 3%	Explore
exhausted T cell	4 studies	88% ± 12%	Explore
precursor cell	4 studies	84% ± 25%	Explore
pancreatic A cell	4 studies	96% ± 6%	Explore
type B pancreatic cell	4 studies	94% ± 9%	Explore
cholangiocyte	4 studies	43% ± 33%	Explore
endothelial cell of sinusoid	4 studies	47% ± 30%	Explore
glomerular endothelial cell	4 studies	80% ± 15%	Explore
kidney connecting tubule epithelial cell	4 studies	93% ± 4%	Explore
podocyte	4 studies	89% ± 11%	Explore
GABAergic amacrine cell	4 studies	41% ± 16%	Explore
glycinergic amacrine cell	4 studies	40% ± 17%	Explore
pro-B cell	4 studies	97% ± 2%	Explore
neuroendocrine cell	4 studies	97% ± 2%	Explore
Schwann cell	4 studies	57% ± 36%	Explore
adventitial cell	4 studies	88% ± 14%	Explore
mucus secreting cell	4 studies	79% ± 31%	Explore
retina horizontal cell	4 studies	44% ± 14%	Explore
keratinocyte	4 studies	85% ± 22%	Explore
inflammatory macrophage	4 studies	84% ± 14%	Explore
acinar cell	4 studies	87% ± 19%	Explore
muscle cell	4 studies	59% ± 20%	Explore
germinal center B cell	4 studies	99% ± 1%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	97% ± 5%	Explore
adipocyte	4 studies	22% ± 3%	Explore
hepatocyte	4 studies	65% ± 30%	Explore
IgM plasma cell	4 studies	93% ± 5%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	79% ± 36%	Explore
T-helper 1 cell	4 studies	100% ± 0%	Explore
squamous epithelial cell	3 studies	60% ± 22%	Explore
pancreatic D cell	3 studies	98% ± 3%	Explore
renal beta-intercalated cell	3 studies	100% ± 0%	Explore
neural crest cell	3 studies	100% ± 0%	Explore
paneth cell	3 studies	95% ± 6%	Explore
retinal bipolar neuron	3 studies	54% ± 29%	Explore
renal principal cell	3 studies	90% ± 5%	Explore
thymocyte	3 studies	100% ± 0%	Explore
extravillous trophoblast	3 studies	100% ± 0%	Explore
placental villous trophoblast	3 studies	100% ± 0%	Explore
common myeloid progenitor	3 studies	71% ± 36%	Explore
serous secreting cell	3 studies	86% ± 8%	Explore
tissue-resident macrophage	3 studies	73% ± 30%	Explore
follicular B cell	3 studies	99% ± 1%	Explore
intraepithelial lymphocyte	3 studies	99% ± 1%	Explore
rod bipolar cell	3 studies	69% ± 17%	Explore
chondrocyte	3 studies	65% ± 22%	Explore
myoepithelial cell	3 studies	99% ± 0%	Explore
luminal cell of prostate epithelium	3 studies	100% ± 0%	Explore
retinal pigment epithelial cell	3 studies	52% ± 18%	Explore
pancreatic ductal cell	3 studies	94% ± 4%	Explore
granulocyte monocyte progenitor cell	3 studies	88% ± 16%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	99% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	98% ± 1%	Explore
progenitor cell of mammary luminal epithelium	3 studies	99% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	19 studies	82% ± 20%	Explore
peripheral blood	19 studies	90% ± 12%	Explore
intestine	15 studies	79% ± 27%	Explore
brain	14 studies	41% ± 21%	Explore
eye	10 studies	61% ± 22%	Explore
liver	8 studies	61% ± 28%	Explore
kidney	8 studies	82% ± 19%	Explore
bone marrow	6 studies	92% ± 8%	Explore
uterus	6 studies	81% ± 28%	Explore
pancreas	5 studies	88% ± 16%	Explore
lymph node	5 studies	93% ± 12%	Explore
placenta	4 studies	90% ± 16%	Explore
heart	4 studies	46% ± 21%	Explore
skin	4 studies	65% ± 31%	Explore
adipose	4 studies	44% ± 30%	Explore
esophagus	4 studies	78% ± 21%	Explore
prostate	4 studies	95% ± 9%	Explore
breast	4 studies	96% ± 3%	Explore
ovary	3 studies	76% ± 32%	Explore
stomach	3 studies	67% ± 19%	Explore
thymus	3 studies	78% ± 30%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	94356.24	21 / 21	100%	2706.89	504 / 504
ovary	100%	159017.64	180 / 180	100%	2361.14	430 / 430
pancreas	100%	83039.18	328 / 328	100%	1643.11	178 / 178
prostate	100%	89739.75	245 / 245	100%	3219.89	502 / 502
stomach	100%	65040.29	359 / 359	100%	2196.11	286 / 286
thymus	100%	69513.05	653 / 653	100%	2494.79	605 / 605
kidney	100%	63116.34	89 / 89	100%	1664.19	900 / 901
breast	100%	103715.64	459 / 459	100%	2068.17	1116 / 1118
uterus	100%	97973.94	170 / 170	100%	2194.50	458 / 459
intestine	100%	77510.35	966 / 966	100%	3089.31	525 / 527
lung	100%	60744.03	576 / 578	100%	1706.04	1153 / 1155
skin	100%	115603.90	1809 / 1809	98%	1590.50	462 / 472
brain	99%	32362.71	2619 / 2642	99%	1256.38	695 / 705
esophagus	100%	77173.75	1445 / 1445	97%	898.62	178 / 183
adrenal gland	100%	55551.10	258 / 258	97%	1148.60	222 / 230
liver	98%	27043.00	222 / 226	98%	1153.43	397 / 406
adipose	100%	91912.01	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	4412.81	29 / 29
spleen	100%	77310.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	1983.68	45 / 45
ureter	0%	0	0 / 0	100%	1597.40	1 / 1
blood vessel	100%	66970.80	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	3389.60	79 / 80
muscle	99%	40033.10	792 / 803	0%	0	0 / 0
heart	96%	35840.95	827 / 861	0%	0	0 / 0
peripheral blood	84%	57747.12	776 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0048821	Biological process	erythrocyte development
GO_0031929	Biological process	TOR signaling
GO_0006412	Biological process	translation
GO_0022605	Biological process	mammalian oogenesis stage
GO_0007369	Biological process	gastrulation
GO_0001890	Biological process	placenta development
GO_0042274	Biological process	ribosomal small subunit biogenesis
GO_0033077	Biological process	T cell differentiation in thymus
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0006924	Biological process	activation-induced cell death of T cells
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0002309	Biological process	T cell proliferation involved in immune response
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0006364	Biological process	rRNA processing
GO_0042593	Biological process	glucose homeostasis
GO_0000082	Biological process	G1/S transition of mitotic cell cycle
GO_0002181	Biological process	cytoplasmic translation
GO_0005730	Cellular component	nucleolus
GO_0022626	Cellular component	cytosolic ribosome
GO_0022627	Cellular component	cytosolic small ribosomal subunit
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0032040	Cellular component	small-subunit processome
GO_0036464	Cellular component	cytoplasmic ribonucleoprotein granule
GO_0005654	Cellular component	nucleoplasm
GO_0030425	Cellular component	dendrite
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0015935	Cellular component	small ribosomal subunit
GO_0005737	Cellular component	cytoplasm
GO_0044297	Cellular component	cell body
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005634	Cellular component	nucleus
GO_0019901	Molecular function	protein kinase binding
GO_0003735	Molecular function	structural constituent of ribosome
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	RPS6
Protein name	40S ribosomal protein S6 Small ribosomal subunit protein eS6 (40S ribosomal protein S6) Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33)
Synonyms	OK/SW-cl.2 hCG_1741512
Description	FUNCTION: Component of the 40S small ribosomal subunit . Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . .
Accessions	P62753 Q96DV6 ENST00000380394.9 A2A3R6 A2A3R5 A2A3R7 ENST00000380384.5 ENST00000315377.4 ENST00000380381.3

RPS6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review