CYB561D2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYB561D2 at tissue level.

III. Associated gene sets

GO_0140576Biological processascorbate homeostasis
GO_0055085Biological processtransmembrane transport
GO_0005783Cellular componentendoplasmic reticulum
GO_0031982Cellular componentvesicle
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0140571Molecular functiontransmembrane ascorbate ferrireductase activity
GO_0140575Molecular functiontransmembrane monodehydroascorbate reductase activity
GO_0016491Molecular functionoxidoreductase activity
GO_0020037Molecular functionheme binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCYB561D2
Protein nameTransmembrane reductase CYB561D2 (EC 7.2.1.3) (Cytochrome b561 domain-containing protein 2) (Putative tumor suppressor protein 101F6)
Synonyms101F6
LUCA12.2
DescriptionFUNCTION: Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment. .

AccessionsENST00000425346.6
O14569
ENST00000232508.9
ENST00000424512.5
ENST00000418577.1