Name | Number of supported studies | Average coverage | |
---|---|---|---|
renal alpha-intercalated cell | 4 studies | 37% ± 6% | |
acinar cell | 3 studies | 51% ± 12% |
Insufficient scRNA-seq data for expression of ERP27 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 99% | 614.15 | 647 / 653 | 80% | 41.69 | 487 / 605 |
pancreas | 100% | 22104.84 | 328 / 328 | 67% | 56.45 | 119 / 178 |
breast | 81% | 189.75 | 370 / 459 | 83% | 42.01 | 931 / 1118 |
lung | 99% | 438.67 | 575 / 578 | 60% | 15.65 | 697 / 1155 |
prostate | 92% | 171.81 | 225 / 245 | 67% | 12.90 | 338 / 502 |
bladder | 86% | 648.52 | 18 / 21 | 68% | 44.84 | 341 / 504 |
kidney | 100% | 1775.16 | 89 / 89 | 30% | 57.91 | 270 / 901 |
ovary | 28% | 28.61 | 51 / 180 | 88% | 76.45 | 377 / 430 |
stomach | 80% | 195.90 | 287 / 359 | 36% | 19.21 | 102 / 286 |
spleen | 100% | 427.66 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 131.04 | 1 / 1 |
peripheral blood | 95% | 317.04 | 884 / 929 | 0% | 0 | 0 / 0 |
intestine | 54% | 88.06 | 521 / 966 | 37% | 11.15 | 196 / 527 |
uterus | 42% | 72.19 | 71 / 170 | 42% | 15.66 | 191 / 459 |
skin | 62% | 86.35 | 1122 / 1809 | 21% | 3.59 | 97 / 472 |
adipose | 73% | 69.58 | 873 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 66% | 54.79 | 169 / 258 | 3% | 0.89 | 8 / 230 |
blood vessel | 63% | 87.62 | 840 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 44% | 46.00 | 639 / 1445 | 19% | 2.20 | 34 / 183 |
liver | 15% | 9.37 | 35 / 226 | 11% | 4.22 | 46 / 406 |
heart | 24% | 15.88 | 208 / 861 | 0% | 0 | 0 / 0 |
brain | 4% | 2.26 | 99 / 2642 | 7% | 0.75 | 47 / 705 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.75 | 3 / 29 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.70 | 4 / 45 |
muscle | 3% | 1.51 | 21 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006457 | Biological process | protein folding |
GO_0006986 | Biological process | response to unfolded protein |
GO_0034976 | Biological process | response to endoplasmic reticulum stress |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0003756 | Molecular function | protein disulfide isomerase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ERP27 |
Protein name | Endoplasmic reticulum resident protein 27 (ER protein 27) (ERp27) (Inactive protein disulfide-isomerase 27) Endoplasmic reticulum protein 27 |
Synonyms | C12orf46 UNQ781/PRO1575 |
Description | FUNCTION: Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates . Binds protein substrates via a hydrophobic pocket in the C-terminal domain . May play a role in the unfolded stress response . . |
Accessions | Q96DN0 ENST00000540097.1 F5GYS6 ENST00000266397.7 |