ATP2A3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	22 studies	26% ± 8%	Explore
memory B cell	13 studies	24% ± 7%	Explore
plasmacytoid dendritic cell	11 studies	24% ± 6%	Explore
naive B cell	10 studies	25% ± 5%	Explore
CD8-positive, alpha-beta T cell	9 studies	19% ± 4%	Explore
goblet cell	8 studies	32% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	21% ± 5%	Explore
natural killer cell	7 studies	20% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	21% ± 4%	Explore
platelet	6 studies	26% ± 4%	Explore
immature B cell	5 studies	39% ± 17%	Explore
T cell	5 studies	18% ± 3%	Explore
mast cell	5 studies	23% ± 6%	Explore
plasma cell	4 studies	30% ± 10%	Explore
plasmablast	4 studies	40% ± 11%	Explore
CD4-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
hematopoietic precursor cell	4 studies	25% ± 6%	Explore
precursor B cell	4 studies	34% ± 15%	Explore
pro-B cell	4 studies	26% ± 8%	Explore
brush cell	4 studies	68% ± 13%	Explore
gamma-delta T cell	4 studies	22% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
ionocyte	3 studies	37% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
mucus secreting cell	3 studies	33% ± 3%	Explore
germinal center B cell	3 studies	26% ± 9%	Explore
megakaryocyte	3 studies	40% ± 5%	Explore
enteroendocrine cell	3 studies	29% ± 8%	Explore
lymphocyte	3 studies	25% ± 5%	Explore
hematopoietic stem cell	3 studies	24% ± 10%	Explore
abnormal cell	3 studies	22% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	4994.16	328 / 328	96%	87.82	170 / 178
stomach	98%	6275.57	353 / 359	97%	66.75	277 / 286
intestine	95%	10322.33	922 / 966	96%	67.38	507 / 527
lung	100%	5560.82	577 / 578	87%	37.63	1002 / 1155
prostate	97%	5055.34	238 / 245	86%	26.40	430 / 502
thymus	93%	3039.22	608 / 653	85%	49.89	515 / 605
bladder	100%	4146.67	21 / 21	75%	31.96	380 / 504
esophagus	88%	3558.49	1269 / 1445	79%	50.06	144 / 183
breast	69%	1803.32	319 / 459	90%	56.70	1011 / 1118
uterus	84%	1835.56	143 / 170	67%	24.02	308 / 459
adrenal gland	93%	2952.72	241 / 258	53%	18.61	122 / 230
kidney	71%	1741.54	63 / 89	69%	16.12	626 / 901
skin	64%	4136.94	1153 / 1809	62%	20.64	293 / 472
lymph node	0%	0	0 / 0	100%	274.42	29 / 29
peripheral blood	100%	16772.17	929 / 929	0%	0	0 / 0
spleen	100%	23031.82	241 / 241	0%	0	0 / 0
blood vessel	93%	3098.76	1236 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	32.13	41 / 45
adipose	65%	1328.33	778 / 1204	0%	0	0 / 0
heart	43%	686.63	366 / 861	0%	0	0 / 0
ovary	18%	341.99	32 / 180	24%	3.44	102 / 430
liver	8%	127.26	17 / 226	21%	4.27	84 / 406
eye	0%	0	0 / 0	28%	3.83	22 / 80
brain	19%	826.04	505 / 2642	3%	0.80	22 / 705
muscle	1%	10.99	5 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0070059	Biological process	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO_0006919	Biological process	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0150104	Biological process	transport across blood-brain barrier
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0006874	Biological process	intracellular calcium ion homeostasis
GO_1900121	Biological process	negative regulation of receptor binding
GO_1903779	Biological process	regulation of cardiac conduction
GO_0006816	Biological process	calcium ion transport
GO_0070588	Biological process	calcium ion transmembrane transport
GO_1903515	Biological process	calcium ion transport from cytosol to endoplasmic reticulum
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0031095	Cellular component	platelet dense tubular network membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0016529	Cellular component	sarcoplasmic reticulum
GO_0033017	Cellular component	sarcoplasmic reticulum membrane
GO_0031090	Cellular component	organelle membrane
GO_0031965	Cellular component	nuclear membrane
GO_0030899	Molecular function	calcium-dependent ATPase activity
GO_0015085	Molecular function	calcium ion transmembrane transporter activity
GO_0005388	Molecular function	P-type calcium transporter activity
GO_0008656	Molecular function	cysteine-type endopeptidase activator activity involved in apoptotic process
GO_0046872	Molecular function	metal ion binding
GO_0044325	Molecular function	transmembrane transporter binding
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

IV. Literature review

[source]

Gene name	ATP2A3
Protein name	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3) ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Synonyms
Description	FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. .
Accessions	A0A0C4DGN1 ENST00000570845.5 Q93084 A0A0C4DGN3 ENST00000309890.11 [Q93084-3] ENST00000397035.7 [Q93084-3] ENST00000352011.7 [Q93084-1] ENST00000572116.1 ENST00000397043.7 [Q93084-4] ENST00000397041.8 [Q93084-2] ENST00000359983.7 [Q93084-5]

ATP2A3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review