TMEM98 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900181Biological processnegative regulation of protein localization to nucleus
GO_0048715Biological processnegative regulation of oligodendrocyte differentiation
GO_0010955Biological processnegative regulation of protein processing
GO_0045063Biological processT-helper 1 cell differentiation
GO_0031642Biological processnegative regulation of myelination
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTMEM98
Protein nameTransmembrane protein 98
Transmembrane protein 98 (Protein TADA1)
SynonymsUNQ536/PRO1079
DescriptionFUNCTION: Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1). .

AccessionsC9J6Q8
J9JIC8
ENST00000578289.5
C9J3Y0
J3QLG7
ENST00000583437.2
J3QS57
ENST00000395149.6
ENST00000579849.6
ENST00000439138.5
ENST00000394642.7
ENST00000261713.8
A0AUK5
Q9Y2Y6