T-helper 1 cell differentiation

I. Literature review

[source]
NameT-helper 1 cell differentiation
IDGO_0045063
collection_id

Biological process

Related synonym

T-helper 1 cell development

Description

The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.

Comment

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

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