TMED3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	20 studies	23% ± 10%	Explore
epithelial cell	11 studies	39% ± 19%	Explore
basal cell	10 studies	32% ± 17%	Explore
plasmacytoid dendritic cell	9 studies	27% ± 8%	Explore
connective tissue cell	8 studies	29% ± 14%	Explore
secretory cell	7 studies	29% ± 9%	Explore
plasma cell	6 studies	30% ± 13%	Explore
plasmablast	6 studies	36% ± 20%	Explore
club cell	6 studies	26% ± 6%	Explore
respiratory goblet cell	6 studies	31% ± 10%	Explore
conventional dendritic cell	6 studies	26% ± 10%	Explore
abnormal cell	6 studies	32% ± 18%	Explore
goblet cell	6 studies	34% ± 9%	Explore
hematopoietic precursor cell	5 studies	33% ± 12%	Explore
hematopoietic stem cell	5 studies	24% ± 7%	Explore
CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
duct epithelial cell	4 studies	35% ± 8%	Explore
squamous epithelial cell	4 studies	39% ± 20%	Explore
pancreatic A cell	4 studies	60% ± 14%	Explore
type B pancreatic cell	4 studies	52% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	16% ± 0%	Explore
classical monocyte	4 studies	21% ± 6%	Explore
mesothelial cell	4 studies	27% ± 17%	Explore
endothelial cell	4 studies	21% ± 7%	Explore
progenitor cell	4 studies	19% ± 3%	Explore
adventitial cell	4 studies	18% ± 4%	Explore
ciliated cell	4 studies	34% ± 10%	Explore
regulatory T cell	4 studies	17% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	27% ± 8%	Explore
natural killer cell	4 studies	21% ± 2%	Explore
CD4-positive, alpha-beta T cell	3 studies	18% ± 0%	Explore
non-classical monocyte	3 studies	28% ± 6%	Explore
extravillous trophoblast	3 studies	45% ± 11%	Explore
placental villous trophoblast	3 studies	46% ± 23%	Explore
B cell	3 studies	19% ± 3%	Explore
myofibroblast cell	3 studies	17% ± 1%	Explore
mucus secreting cell	3 studies	62% ± 15%	Explore
serous secreting cell	3 studies	59% ± 29%	Explore
macrophage	3 studies	24% ± 7%	Explore
GABAergic neuron	3 studies	25% ± 7%	Explore
glutamatergic neuron	3 studies	30% ± 8%	Explore
dendritic cell	3 studies	44% ± 10%	Explore
pancreatic ductal cell	3 studies	35% ± 10%	Explore
granulocyte monocyte progenitor cell	3 studies	37% ± 15%	Explore
intestinal crypt stem cell	3 studies	21% ± 4%	Explore
progenitor cell of mammary luminal epithelium	3 studies	26% ± 8%	Explore
luminal cell of prostate epithelium	3 studies	24% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	5 studies	32% ± 11%	Explore
pancreas	4 studies	51% ± 19%	Explore
peripheral blood	3 studies	22% ± 2%	Explore
placenta	3 studies	35% ± 9%	Explore
brain	3 studies	22% ± 3%	Explore
intestine	3 studies	25% ± 10%	Explore
liver	3 studies	21% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	7636.83	328 / 328	100%	22.52	178 / 178
prostate	100%	5189.16	245 / 245	100%	45.43	502 / 502
thymus	100%	5816.00	653 / 653	100%	27.63	604 / 605
skin	100%	7328.71	1809 / 1809	100%	26.32	471 / 472
uterus	100%	2606.19	170 / 170	100%	22.08	458 / 459
bladder	100%	3053.86	21 / 21	99%	25.36	499 / 504
stomach	99%	4231.85	357 / 359	99%	17.29	284 / 286
ovary	99%	2229.80	179 / 180	98%	16.02	423 / 430
intestine	100%	2371.23	962 / 966	98%	20.64	517 / 527
kidney	100%	2510.22	89 / 89	97%	11.39	875 / 901
esophagus	98%	4217.35	1416 / 1445	99%	14.22	181 / 183
lung	97%	2458.98	562 / 578	100%	22.20	1151 / 1155
breast	95%	2919.65	438 / 459	100%	32.73	1115 / 1118
adrenal gland	98%	1949.20	253 / 258	92%	13.18	211 / 230
brain	90%	1693.35	2389 / 2642	97%	8.97	687 / 705
lymph node	0%	0	0 / 0	100%	14.74	29 / 29
spleen	100%	2656.27	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	14.59	45 / 45
ureter	0%	0	0 / 0	100%	29.62	1 / 1
blood vessel	100%	3584.30	1331 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	17.96	79 / 80
adipose	94%	1861.57	1127 / 1204	0%	0	0 / 0
heart	86%	1745.49	738 / 861	0%	0	0 / 0
peripheral blood	72%	1575.53	673 / 929	0%	0	0 / 0
liver	23%	269.18	51 / 226	48%	6.42	195 / 406
muscle	2%	25.33	19 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007030	Biological process	Golgi organization
GO_0006886	Biological process	intracellular protein transport
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139	Cellular component	Golgi membrane
GO_0030126	Cellular component	COPI vesicle coat
GO_0005783	Cellular component	endoplasmic reticulum
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030133	Cellular component	transport vesicle
GO_0038024	Molecular function	cargo receptor activity

IV. Literature review

[source]

Gene name	TMED3
Protein name	Transmembrane p24 trafficking protein 3 Testis tissue sperm-binding protein Li 48e (Transmembrane emp24 protein transport domain containing 3, isoform CRA_a) Transmembrane emp24 domain-containing protein 3 (Membrane protein p24B) (p24 family protein gamma-4) (p24gamma4) (p26) Transmembrane emp24 protein transport domain containing 3, isoform CRA_b (Transmembrane p24 trafficking protein 3)
Synonyms	hCG_24828 C15orf22 UNQ5357/PRO1078
Description	FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. .
Accessions	ENST00000543455.1 ENST00000536821.5 G3V1J9 Q9Y3Q3 A0A140VKD1 F5H4M7 ENST00000299705.10 [Q9Y3Q3-1] ENST00000424155.6 [Q9Y3Q3-2]

TMED3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review