UBXN4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	43 studies	38% ± 13%	Explore
fibroblast	41 studies	39% ± 14%	Explore
B cell	37 studies	31% ± 9%	Explore
macrophage	35 studies	31% ± 10%	Explore
natural killer cell	35 studies	34% ± 10%	Explore
T cell	32 studies	33% ± 11%	Explore
pericyte	32 studies	32% ± 12%	Explore
CD8-positive, alpha-beta T cell	32 studies	35% ± 12%	Explore
CD4-positive, alpha-beta T cell	31 studies	34% ± 10%	Explore
smooth muscle cell	29 studies	28% ± 9%	Explore
conventional dendritic cell	25 studies	33% ± 14%	Explore
regulatory T cell	25 studies	39% ± 10%	Explore
plasma cell	23 studies	42% ± 18%	Explore
epithelial cell	22 studies	43% ± 21%	Explore
classical monocyte	22 studies	32% ± 11%	Explore
non-classical monocyte	21 studies	31% ± 11%	Explore
memory B cell	20 studies	31% ± 6%	Explore
basal cell	20 studies	42% ± 15%	Explore
mast cell	19 studies	32% ± 13%	Explore
monocyte	19 studies	30% ± 7%	Explore
endothelial cell of lymphatic vessel	19 studies	36% ± 11%	Explore
mature NK T cell	19 studies	33% ± 8%	Explore
plasmacytoid dendritic cell	19 studies	45% ± 12%	Explore
ciliated cell	19 studies	52% ± 18%	Explore
naive B cell	19 studies	31% ± 8%	Explore
astrocyte	18 studies	33% ± 14%	Explore
connective tissue cell	17 studies	39% ± 12%	Explore
gamma-delta T cell	17 studies	38% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	31% ± 10%	Explore
dendritic cell	15 studies	38% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	34% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	36% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	36% ± 10%	Explore
capillary endothelial cell	14 studies	32% ± 10%	Explore
myofibroblast cell	14 studies	37% ± 11%	Explore
mucosal invariant T cell	13 studies	34% ± 8%	Explore
endothelial cell of vascular tree	13 studies	33% ± 8%	Explore
myeloid cell	13 studies	32% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	41% ± 9%	Explore
secretory cell	12 studies	47% ± 10%	Explore
oligodendrocyte	12 studies	33% ± 13%	Explore
vein endothelial cell	12 studies	34% ± 7%	Explore
oligodendrocyte precursor cell	12 studies	35% ± 16%	Explore
type I pneumocyte	11 studies	35% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	35% ± 10%	Explore
plasmablast	11 studies	58% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	41% ± 10%	Explore
club cell	11 studies	38% ± 13%	Explore
endothelial cell of artery	11 studies	32% ± 7%	Explore
microglial cell	11 studies	31% ± 10%	Explore
type II pneumocyte	10 studies	32% ± 13%	Explore
glutamatergic neuron	10 studies	43% ± 26%	Explore
progenitor cell	10 studies	39% ± 14%	Explore
abnormal cell	10 studies	43% ± 15%	Explore
mesothelial cell	10 studies	44% ± 18%	Explore
leukocyte	9 studies	31% ± 9%	Explore
GABAergic neuron	9 studies	39% ± 22%	Explore
neuron	9 studies	46% ± 16%	Explore
goblet cell	9 studies	39% ± 17%	Explore
retinal rod cell	9 studies	55% ± 15%	Explore
adipocyte	9 studies	25% ± 5%	Explore
alveolar macrophage	8 studies	29% ± 7%	Explore
innate lymphoid cell	8 studies	30% ± 9%	Explore
respiratory goblet cell	8 studies	45% ± 16%	Explore
retinal cone cell	8 studies	57% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	40% ± 13%	Explore
IgA plasma cell	7 studies	31% ± 14%	Explore
IgG plasma cell	7 studies	32% ± 13%	Explore
amacrine cell	7 studies	32% ± 14%	Explore
T follicular helper cell	7 studies	35% ± 7%	Explore
ionocyte	6 studies	43% ± 14%	Explore
mononuclear phagocyte	6 studies	32% ± 13%	Explore
epithelial cell of proximal tubule	6 studies	23% ± 8%	Explore
kidney loop of Henle epithelial cell	6 studies	30% ± 12%	Explore
renal alpha-intercalated cell	6 studies	36% ± 4%	Explore
interneuron	6 studies	43% ± 21%	Explore
hematopoietic stem cell	6 studies	40% ± 13%	Explore
lymphocyte	6 studies	37% ± 14%	Explore
precursor B cell	6 studies	41% ± 11%	Explore
mucus secreting cell	6 studies	26% ± 6%	Explore
Mueller cell	6 studies	36% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	42% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	30% ± 8%	Explore
hematopoietic precursor cell	5 studies	49% ± 20%	Explore
exhausted T cell	5 studies	50% ± 7%	Explore
enterocyte	5 studies	31% ± 7%	Explore
enteroendocrine cell	5 studies	45% ± 13%	Explore
transit amplifying cell	5 studies	36% ± 18%	Explore
retinal bipolar neuron	5 studies	41% ± 17%	Explore
glial cell	5 studies	31% ± 18%	Explore
retinal ganglion cell	5 studies	39% ± 20%	Explore
pro-B cell	5 studies	45% ± 7%	Explore
brush cell	5 studies	36% ± 18%	Explore
immature B cell	5 studies	40% ± 13%	Explore
retina horizontal cell	5 studies	34% ± 11%	Explore
adventitial cell	5 studies	34% ± 10%	Explore
cardiac muscle cell	5 studies	22% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	43% ± 13%	Explore
hepatocyte	5 studies	46% ± 25%	Explore
erythrocyte	5 studies	31% ± 16%	Explore
CD4-positive helper T cell	4 studies	32% ± 10%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	29% ± 9%	Explore
deuterosomal cell	4 studies	44% ± 9%	Explore
duct epithelial cell	4 studies	38% ± 6%	Explore
neutrophil	4 studies	18% ± 2%	Explore
precursor cell	4 studies	50% ± 7%	Explore
pancreatic A cell	4 studies	62% ± 21%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	41% ± 7%	Explore
intestinal crypt stem cell	4 studies	28% ± 8%	Explore
granule cell	4 studies	24% ± 6%	Explore
ON-bipolar cell	4 studies	32% ± 12%	Explore
erythroblast	4 studies	36% ± 19%	Explore
OFF-bipolar cell	4 studies	27% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	57% ± 13%	Explore
granulocyte	4 studies	28% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	36% ± 13%	Explore
keratinocyte	4 studies	26% ± 6%	Explore
T-helper 17 cell	4 studies	35% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	39% ± 16%	Explore
hillock cell	3 studies	27% ± 15%	Explore
squamous epithelial cell	3 studies	47% ± 22%	Explore
platelet	3 studies	16% ± 1%	Explore
pancreatic D cell	3 studies	65% ± 28%	Explore
type B pancreatic cell	3 studies	76% ± 14%	Explore
glomerular endothelial cell	3 studies	33% ± 6%	Explore
neural crest cell	3 studies	41% ± 3%	Explore
GABAergic interneuron	3 studies	24% ± 4%	Explore
extravillous trophoblast	3 studies	42% ± 9%	Explore
placental villous trophoblast	3 studies	64% ± 3%	Explore
retinal pigment epithelial cell	3 studies	47% ± 17%	Explore
serous secreting cell	3 studies	34% ± 7%	Explore
tissue-resident macrophage	3 studies	27% ± 5%	Explore
glycinergic amacrine cell	3 studies	22% ± 5%	Explore
rod bipolar cell	3 studies	49% ± 6%	Explore
acinar cell	3 studies	51% ± 30%	Explore
germinal center B cell	3 studies	29% ± 4%	Explore
intermediate monocyte	3 studies	46% ± 20%	Explore
myoepithelial cell	3 studies	40% ± 18%	Explore
IgM plasma cell	3 studies	37% ± 13%	Explore
muscle cell	3 studies	37% ± 13%	Explore
pancreatic ductal cell	3 studies	70% ± 20%	Explore
group 3 innate lymphoid cell	3 studies	49% ± 12%	Explore
T-helper 1 cell	3 studies	45% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	36% ± 8%	Explore
double negative thymocyte	3 studies	55% ± 18%	Explore
progenitor cell of mammary luminal epithelium	3 studies	35% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	39% ± 13%	Explore
brain	18 studies	35% ± 18%	Explore
peripheral blood	17 studies	35% ± 11%	Explore
intestine	11 studies	30% ± 13%	Explore
eye	11 studies	42% ± 15%	Explore
kidney	8 studies	32% ± 9%	Explore
liver	6 studies	38% ± 18%	Explore
lymph node	5 studies	39% ± 9%	Explore
pancreas	4 studies	60% ± 25%	Explore
bone marrow	4 studies	30% ± 9%	Explore
heart	4 studies	23% ± 5%	Explore
uterus	4 studies	47% ± 17%	Explore
breast	4 studies	36% ± 5%	Explore
prostate	4 studies	30% ± 12%	Explore
adipose	4 studies	31% ± 7%	Explore
placenta	3 studies	50% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6384.32	1445 / 1445	100%	136.13	183 / 183
ovary	100%	8389.56	180 / 180	100%	88.43	430 / 430
lung	100%	8405.30	577 / 578	100%	116.03	1155 / 1155
breast	100%	8655.62	459 / 459	100%	133.50	1116 / 1118
brain	100%	5305.89	2636 / 2642	100%	91.07	704 / 705
bladder	100%	7163.52	21 / 21	100%	93.98	502 / 504
prostate	100%	8031.67	245 / 245	100%	120.07	500 / 502
intestine	100%	7652.66	966 / 966	99%	102.48	523 / 527
thymus	100%	10159.40	653 / 653	99%	111.42	600 / 605
uterus	100%	7816.97	170 / 170	99%	96.07	455 / 459
pancreas	100%	7155.93	328 / 328	99%	89.71	176 / 178
stomach	100%	6572.04	359 / 359	99%	107.93	282 / 286
kidney	100%	6363.40	89 / 89	98%	90.86	884 / 901
adrenal gland	100%	9511.94	258 / 258	97%	69.58	224 / 230
liver	100%	6852.34	226 / 226	96%	67.71	390 / 406
skin	100%	8778.71	1809 / 1809	92%	69.72	432 / 472
adipose	100%	8380.43	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6784.09	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	64.58	29 / 29
muscle	100%	7158.86	803 / 803	0%	0	0 / 0
spleen	100%	7732.64	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	89.07	45 / 45
ureter	0%	0	0 / 0	100%	34.28	1 / 1
heart	98%	4349.05	840 / 861	0%	0	0 / 0
peripheral blood	88%	4833.77	819 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	60%	28.23	48 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006986	Biological process	response to unfolded protein
GO_0036503	Biological process	ERAD pathway
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005635	Cellular component	nuclear envelope
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005515	Molecular function	protein binding

Gene name	UBXN4
Protein name	UBX domain protein 4 UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) UBX domain protein 4 (UBXN4 protein)
Synonyms	UBXD2 KIAA0242 UBXDC1
Description	FUNCTION: Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD . .
Accessions	Q92575 ENST00000426921.5 Q6PJ80 F8WB86 ENST00000272638.14 C9JLR4 ENST00000415164.5 ENST00000416538.5

UBXN4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review