SLC22A13 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC22A13 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	228.40	89 / 89	38%	1.83	343 / 901
bladder	100%	9.86	21 / 21	0%	0.00	1 / 504
peripheral blood	94%	11.42	875 / 929	0%	0	0 / 0
thymus	94%	8.38	613 / 653	0%	0	0 / 605
lung	93%	8.10	537 / 578	1%	0.01	7 / 1155
esophagus	89%	10.62	1286 / 1445	4%	0.05	7 / 183
intestine	92%	7.71	886 / 966	1%	0.02	3 / 527
muscle	92%	8.97	735 / 803	0%	0	0 / 0
spleen	91%	7.46	220 / 241	0%	0	0 / 0
uterus	91%	6.09	154 / 170	0%	0.00	1 / 459
prostate	90%	8.32	221 / 245	0%	0.00	1 / 502
stomach	88%	6.73	317 / 359	2%	0.03	6 / 286
blood vessel	90%	7.06	1200 / 1335	0%	0	0 / 0
skin	89%	8.65	1616 / 1809	0%	0.02	1 / 472
adrenal gland	88%	6.47	226 / 258	0%	0	0 / 230
pancreas	84%	5.34	276 / 328	1%	0.01	1 / 178
liver	83%	5.30	188 / 226	1%	0.01	3 / 406
adipose	83%	5.40	996 / 1204	0%	0	0 / 0
breast	82%	5.46	377 / 459	1%	0.01	6 / 1118
brain	79%	8.83	2098 / 2642	0%	0.00	1 / 705
heart	76%	4.63	654 / 861	0%	0	0 / 0
ovary	76%	4.29	136 / 180	0%	0.00	1 / 430
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_2001142	Biological process	nicotinate transport
GO_0045922	Biological process	negative regulation of fatty acid metabolic process
GO_0002854	Biological process	positive regulation of T cell mediated cytotoxicity directed against tumor cell target
GO_0015747	Biological process	urate transport
GO_0034356	Biological process	NAD biosynthesis via nicotinamide riboside salvage pathway
GO_0055085	Biological process	transmembrane transport
GO_0016324	Cellular component	apical plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005794	Cellular component	Golgi apparatus
GO_0005886	Cellular component	plasma membrane
GO_0090416	Molecular function	nicotinate transmembrane transporter activity
GO_0015143	Molecular function	urate transmembrane transporter activity

Gene name	SLC22A13
Protein name	Solute carrier family 22 member 13 Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3) (ORCTL3)
Synonyms	OCTL1 ORCTL3
Description	FUNCTION: Anion antiporter that mediates the transport of urate, orotate and nicotinate in exchange for organic or inorganic anions . Translocates urate and orotate across the apical membrane of proximal tubule epithelial cells and involved in urate renal reabsorption . Possibly involved in orotate renal reabsorption and nicotinate intestinal reabsorption . Mediates urate uptake by an exchange with organic anions such as (S)-lactate, succinate, glutathione and nicotinate . Urate and orotate transports are Cl(-)-dependent . Shows similar transport characteristics as the urate/orotate renal antiporter SLC22A12/URAT1 and may act as a compensator of SLC22A12/URAT1 in certain conditions (Probable). .
Accessions	A0A3B3ITC0 H0Y4Y1 Q9Y226 ENST00000649621.1 ENST00000415844.1 ENST00000311856.9 [Q9Y226-1]

SLC22A13 report