FNDC5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FNDC5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FNDC5 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0090336Biological processpositive regulation of brown fat cell differentiation
GO_0008150Biological processbiological_process
GO_0014850Biological processresponse to muscle activity
GO_0005778Cellular componentperoxisomal membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0005179Molecular functionhormone activity
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameFNDC5
Protein nameFibronectin type III domain-containing protein 5
Fibronectin type III domain containing 5
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
SynonymsFRCP2
DescriptionFUNCTION: [Irisin]: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. .

AccessionsENST00000710568.1
A0A0A0MRR6
A0A3B3ITP1
A0AA34QVI5
ENST00000649537.2
ENST00000373471
ENST00000373471.9 [Q8NAU1-1]
Q8NAU1
ENST00000496770.1 [Q8NAU1-3]