ALG1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ALG1 at tissue level.

III. Associated gene sets

GO_0006486Biological processprotein glycosylation
GO_0006487Biological processprotein N-linked glycosylation
GO_0006488Biological processdolichol-linked oligosaccharide biosynthetic process
GO_0005783Cellular componentendoplasmic reticulum
GO_0098554Cellular componentcytoplasmic side of endoplasmic reticulum membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004578Molecular functionchitobiosyldiphosphodolichol beta-mannosyltransferase activity
GO_0000030Molecular functionmannosyltransferase activity

IV. Literature review

[source]
Gene nameALG1
Protein nameALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (Mannosyltransferase-1) (MT-1) (hMat-1)
SynonymsUNQ861/PRO1870
HMT1
HMAT1
PSEC0061
DescriptionFUNCTION: Catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation. .

AccessionsA0A804HHW1
ENST00000591783.5
A0A804HKU4
A0A804HJQ1
ENST00000684190.1
ENST00000650085.1
ENST00000682327.1
A0A804HJL6
K7EPU3
ENST00000591822.5
Q9BT22
ENST00000683433.1
ENST00000684008.1
ENST00000586840.1
A0A804HLB7
ENST00000262374.10 [Q9BT22-1]
A0A804HKX7
K7EID2
A0A804HJE3
A0A804HKK4
ENST00000682797.1
ENST00000544428.1 [Q9BT22-2]
ENST00000588623.5 [Q9BT22-2]
ENST00000683710.1
ENST00000682020.1
ENST00000683739.1 [Q9BT22-2]
ENST00000682985.1
A0A804HKJ4
A0A804HIG6
ENST00000682206.1
K7EQK1
ENST00000684335.1