PLSCR2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLSCR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	20.49	89 / 89	12%	0.20	112 / 901
pancreas	99%	18.93	326 / 328	3%	0.05	6 / 178
lung	92%	9.23	531 / 578	9%	0.18	106 / 1155
thymus	99%	15.47	648 / 653	0%	0.00	2 / 605
ovary	75%	4.23	135 / 180	20%	0.30	86 / 430
prostate	92%	8.66	226 / 245	2%	0.03	10 / 502
esophagus	78%	4.85	1131 / 1445	13%	0.23	23 / 183
stomach	86%	5.64	308 / 359	5%	0.09	14 / 286
spleen	88%	7.20	212 / 241	0%	0	0 / 0
breast	78%	7.25	360 / 459	6%	0.11	70 / 1118
intestine	76%	7.45	735 / 966	6%	0.10	32 / 527
bladder	71%	5.71	15 / 21	6%	0.13	29 / 504
uterus	68%	3.51	115 / 170	4%	0.06	19 / 459
liver	68%	3.45	154 / 226	2%	0.03	8 / 406
blood vessel	70%	3.64	929 / 1335	0%	0	0 / 0
skin	66%	3.50	1186 / 1809	0%	0	0 / 472
adipose	65%	3.55	781 / 1204	0%	0	0 / 0
peripheral blood	58%	6.17	541 / 929	0%	0	0 / 0
adrenal gland	53%	1.88	136 / 258	0%	0	0 / 230
heart	47%	1.89	405 / 861	0%	0	0 / 0
brain	34%	1.34	890 / 2642	0%	0	0 / 705
muscle	23%	0.86	188 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0017121	Biological process	plasma membrane phospholipid scrambling
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005654	Cellular component	nucleoplasm
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005886	Cellular component	plasma membrane
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding
GO_0017128	Molecular function	phospholipid scramblase activity

Gene name	PLSCR2
Protein name	Phospholipid scramblase Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)
Synonyms
Description	FUNCTION: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.; FUNCTION: Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain. FUNCTION: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. . FUNCTION: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. .
Accessions	ENST00000696113.1 [Q9NRY7-1] ENST00000497985.5 [Q9NRY7-2] ENST00000336685.6 [Q9NRY7-1] C9J636 ENST00000696120.1 [Q9NRY7-1] ENST00000463633.5 F8WEZ1 ENST00000610787.5 [Q9NRY7-1] ENST00000696119.1 [Q9NRY7-2] Q9NRY7 ENST00000489015.1 ENST00000613069.4 [Q9NRY7-3]

PLSCR2 report