TSPO2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TSPO2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TSPO2 at tissue level.

III. Associated gene sets

GO_0032367Biological processintracellular cholesterol transport
GO_0043353Biological processenucleate erythrocyte differentiation
GO_0098739Biological processimport across plasma membrane
GO_0034389Biological processlipid droplet organization
GO_0140484Biological process5-aminolevulinic acid import across plasma membrane
GO_0031090Cellular componentorganelle membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0015485Molecular functioncholesterol binding
GO_0005515Molecular functionprotein binding
GO_0140485Molecular function5-aminolevulinic acid transmembrane transporter activity

IV. Literature review

[source]
Gene nameTSPO2
Protein nameTranslocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1)
SynonymsBZRPL1
DescriptionFUNCTION: Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum . Required to meet cholesterol demands during erythropoietic differentiation . May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid . .

AccessionsENST00000373158.6 [Q5TGU0-2]
ENST00000373161.6 [Q5TGU0-1]
Q5TGU0
ENST00000470917.1 [Q5TGU0-1]