Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasmacytoid dendritic cell | 15 studies | 26% ± 9% | |
| plasma cell | 9 studies | 23% ± 7% | |
| plasmablast | 7 studies | 40% ± 22% | |
| epithelial cell | 5 studies | 27% ± 13% | |
| type B pancreatic cell | 3 studies | 37% ± 15% | |
| endothelial cell | 3 studies | 19% ± 2% | |
| macrophage | 3 studies | 21% ± 3% | |
| dendritic cell | 3 studies | 22% ± 3% | |
| goblet cell | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of HYOU1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4122.00 | 1443 / 1445 | 100% | 85.59 | 183 / 183 |
| stomach | 100% | 5490.87 | 359 / 359 | 100% | 82.41 | 285 / 286 |
| lung | 100% | 6752.72 | 578 / 578 | 99% | 97.28 | 1146 / 1155 |
| intestine | 100% | 4640.00 | 964 / 966 | 99% | 84.49 | 521 / 527 |
| pancreas | 100% | 10634.45 | 328 / 328 | 98% | 65.47 | 174 / 178 |
| ovary | 99% | 4706.96 | 179 / 180 | 98% | 71.18 | 421 / 430 |
| skin | 100% | 4892.50 | 1801 / 1809 | 97% | 91.35 | 460 / 472 |
| prostate | 100% | 5402.87 | 245 / 245 | 97% | 113.96 | 487 / 502 |
| breast | 100% | 4475.23 | 458 / 459 | 97% | 75.51 | 1082 / 1118 |
| brain | 98% | 4561.11 | 2586 / 2642 | 98% | 59.69 | 694 / 705 |
| bladder | 100% | 5382.24 | 21 / 21 | 95% | 69.34 | 479 / 504 |
| uterus | 100% | 5473.31 | 170 / 170 | 94% | 59.98 | 430 / 459 |
| thymus | 100% | 11514.14 | 653 / 653 | 93% | 69.53 | 564 / 605 |
| kidney | 100% | 5896.67 | 89 / 89 | 90% | 49.86 | 815 / 901 |
| liver | 97% | 10126.39 | 219 / 226 | 93% | 68.58 | 378 / 406 |
| adrenal gland | 100% | 5285.64 | 257 / 258 | 81% | 72.66 | 187 / 230 |
| spleen | 100% | 5657.95 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 18.09 | 1 / 1 |
| blood vessel | 100% | 5755.41 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 4269.95 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 52.31 | 43 / 45 |
| heart | 94% | 4445.25 | 811 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 28.68 | 68 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 65.45 | 24 / 29 |
| muscle | 69% | 1455.46 | 557 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 66% | 4297.88 | 613 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002931 | Biological process | response to ischemia |
| GO_1903382 | Biological process | negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway |
| GO_0034976 | Biological process | response to endoplasmic reticulum stress |
| GO_0006457 | Biological process | protein folding |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_1903298 | Biological process | negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway |
| GO_0071456 | Biological process | cellular response to hypoxia |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0005790 | Cellular component | smooth endoplasmic reticulum |
| GO_0071682 | Cellular component | endocytic vesicle lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0034663 | Cellular component | endoplasmic reticulum chaperone complex |
| GO_0000774 | Molecular function | adenyl-nucleotide exchange factor activity |
| GO_0051082 | Molecular function | unfolded protein binding |
| GO_0140662 | Molecular function | ATP-dependent protein folding chaperone |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HYOU1 |
| Protein name | Hypoxia up-regulated protein 1 Hypoxia up-regulated 1 Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) Hypoxia up-regulated 1 (Hypoxia up-regulated protein 1) |
| Synonyms | GRP170 ORP150 |
| Description | FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. . |
| Accessions | ENST00000614711.5 [Q9Y4L1-1] J3QL06 ENST00000530473.5 ENST00000694934.1 ENST00000629044 ENST00000614711.4 ENST00000629679 A0A0G2JR88 A0A494C039 J3KTF1 ENST00000534233.5 A0A0G2JRS0 ENST00000628429 ENST00000694937.1 A0A0G2JRT9 A0A8Q3SHG4 K7EQK2 ENST00000610597.2 ENST00000627731 ENST00000694933.1 Q9Y4L1 ENST00000532421.6 Q05D91 ENST00000543287.5 ENST00000626576 ENST00000630070 ENST00000629353 ENST00000652093.1 ENST00000625612 J3QLE9 A0A8Q3SHP7 ENST00000694935.1 ENST00000531968.5 ENST00000626494 Q6IN67 ENST00000628600 A0A8Q3SHL4 A0A0G2JR71 J3QQH7 ENST00000621959.4 ENST00000534233.6 [Q9Y4L1-1] ENST00000628974 ENST00000627494 ENST00000617285.5 [Q9Y4L1-1] E9PJ21 ENST00000694932.1 Q9BST8 ENST00000532519.7 ENST00000612687.4 A0A087WWI4 ENST00000628120 A0A0G2JRG7 ENST00000530467.6 ENST00000694928.1 ENST00000530473.6 [Q9Y4L1-1] ENST00000629227 J3KSR2 ENST00000630669.3 [Q9Y4L1-1] A0A087X054 ENST00000527038.7 |
