UBE2G2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	18 studies	23% ± 8%	Explore
B cell	11 studies	20% ± 5%	Explore
natural killer cell	11 studies	20% ± 4%	Explore
fibroblast	11 studies	21% ± 6%	Explore
CD8-positive, alpha-beta T cell	11 studies	20% ± 5%	Explore
astrocyte	10 studies	32% ± 15%	Explore
naive B cell	9 studies	18% ± 3%	Explore
adipocyte	9 studies	31% ± 12%	Explore
CD4-positive, alpha-beta T cell	8 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	24% ± 9%	Explore
epithelial cell	8 studies	34% ± 15%	Explore
plasmacytoid dendritic cell	8 studies	23% ± 6%	Explore
mucosal invariant T cell	7 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	7 studies	32% ± 14%	Explore
gamma-delta T cell	7 studies	23% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	22% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	21% ± 6%	Explore
regulatory T cell	6 studies	18% ± 2%	Explore
ciliated cell	6 studies	24% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	21% ± 6%	Explore
memory B cell	6 studies	18% ± 4%	Explore
macrophage	6 studies	24% ± 6%	Explore
oligodendrocyte	6 studies	25% ± 7%	Explore
T cell	5 studies	17% ± 1%	Explore
type I pneumocyte	5 studies	19% ± 5%	Explore
microglial cell	5 studies	25% ± 6%	Explore
retinal rod cell	5 studies	19% ± 2%	Explore
basal cell	5 studies	25% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	19% ± 7%	Explore
pericyte	5 studies	20% ± 5%	Explore
endothelial cell of lymphatic vessel	4 studies	24% ± 4%	Explore
leukocyte	4 studies	18% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	26% ± 7%	Explore
mature NK T cell	4 studies	19% ± 2%	Explore
myeloid cell	4 studies	26% ± 6%	Explore
retinal cone cell	4 studies	26% ± 8%	Explore
lymphocyte	4 studies	24% ± 6%	Explore
hepatocyte	4 studies	36% ± 18%	Explore
glutamatergic neuron	4 studies	41% ± 26%	Explore
dendritic cell	4 studies	32% ± 19%	Explore
abnormal cell	4 studies	25% ± 9%	Explore
smooth muscle cell	4 studies	20% ± 3%	Explore
interneuron	4 studies	38% ± 21%	Explore
classical monocyte	3 studies	33% ± 12%	Explore
hematopoietic precursor cell	3 studies	28% ± 11%	Explore
non-classical monocyte	3 studies	32% ± 9%	Explore
plasmablast	3 studies	37% ± 15%	Explore
retina horizontal cell	3 studies	20% ± 1%	Explore
cardiac muscle cell	3 studies	21% ± 1%	Explore
secretory cell	3 studies	19% ± 4%	Explore
endothelial cell of vascular tree	3 studies	22% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	23% ± 9%	Explore
muscle cell	3 studies	28% ± 14%	Explore
type II pneumocyte	3 studies	26% ± 8%	Explore
GABAergic neuron	3 studies	42% ± 21%	Explore
myofibroblast cell	3 studies	21% ± 5%	Explore
goblet cell	3 studies	29% ± 12%	Explore
transit amplifying cell	3 studies	30% ± 13%	Explore
erythroblast	3 studies	29% ± 8%	Explore
double negative thymocyte	3 studies	26% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	9 studies	31% ± 19%	Explore
peripheral blood	8 studies	23% ± 10%	Explore
lung	5 studies	21% ± 3%	Explore
eye	4 studies	24% ± 7%	Explore
liver	4 studies	27% ± 10%	Explore
heart	3 studies	18% ± 3%	Explore
adipose	3 studies	26% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	7578.25	459 / 459	100%	46.08	1118 / 1118
intestine	100%	7858.46	966 / 966	100%	32.94	527 / 527
pancreas	100%	5317.25	328 / 328	100%	33.47	178 / 178
prostate	100%	7587.07	245 / 245	100%	39.94	502 / 502
skin	100%	6549.32	1809 / 1809	100%	50.11	472 / 472
stomach	100%	5863.53	359 / 359	100%	29.69	286 / 286
uterus	100%	7579.77	170 / 170	100%	38.36	459 / 459
lung	100%	7134.02	578 / 578	100%	35.61	1154 / 1155
brain	100%	4760.40	2638 / 2642	100%	55.02	705 / 705
bladder	100%	7835.29	21 / 21	100%	33.68	503 / 504
thymus	100%	7768.86	653 / 653	100%	40.16	603 / 605
kidney	100%	6594.93	89 / 89	100%	38.22	898 / 901
esophagus	100%	7307.96	1445 / 1445	99%	25.55	182 / 183
liver	100%	5184.85	226 / 226	99%	24.25	403 / 406
ovary	100%	6875.62	180 / 180	99%	27.45	425 / 430
adrenal gland	100%	7688.36	258 / 258	99%	30.20	227 / 230
adipose	100%	8028.48	1204 / 1204	0%	0	0 / 0
blood vessel	100%	7345.55	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	42.23	29 / 29
muscle	100%	8071.63	803 / 803	0%	0	0 / 0
spleen	100%	8712.18	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	32.55	45 / 45
ureter	0%	0	0 / 0	100%	22.19	1 / 1
heart	99%	5474.22	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	43.31	79 / 80
peripheral blood	83%	2971.87	768 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1904153	Biological process	negative regulation of retrograde protein transport, ER to cytosol
GO_0006511	Biological process	ubiquitin-dependent protein catabolic process
GO_0070936	Biological process	protein K48-linked ubiquitination
GO_0036503	Biological process	ERAD pathway
GO_0035458	Biological process	cellular response to interferon-beta
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005811	Cellular component	lipid droplet
GO_0004842	Molecular function	ubiquitin-protein transferase activity
GO_0061631	Molecular function	ubiquitin conjugating enzyme activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0005524	Molecular function	ATP binding

IV. Literature review

[source]

Gene name	UBE2G2
Protein name	Ubiquitin conjugating enzyme E2 G2 E2 ubiquitin-conjugating enzyme (EC 2.3.2.23) Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Synonyms	UBC7
Description	FUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins . In vitro catalyzes 'Lys-48'-linked polyubiquitination . Involved in endoplasmic reticulum-associated degradation (ERAD) . Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation . .
Accessions	ENST00000330942.9 [P60604-2] P60604 F8WCB9 ENST00000345496.7 [P60604-1] ENST00000491513.5 F8WDB1 ENST00000478200.1

UBE2G2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review