I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 28% ± 5% | |
| plasma cell | 3 studies | 25% ± 12% | |
| goblet cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 28% ± 5% | |
| plasma cell | 3 studies | 25% ± 12% | |
| goblet cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of MOGS at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3443.04 | 1445 / 1445 | 100% | 59.68 | 183 / 183 |
| liver | 100% | 4040.57 | 226 / 226 | 100% | 59.53 | 406 / 406 |
| ovary | 100% | 3726.03 | 180 / 180 | 100% | 68.61 | 430 / 430 |
| pancreas | 100% | 5201.06 | 328 / 328 | 100% | 71.69 | 178 / 178 |
| skin | 100% | 4673.25 | 1809 / 1809 | 100% | 85.99 | 472 / 472 |
| uterus | 100% | 4027.75 | 170 / 170 | 100% | 80.07 | 459 / 459 |
| lung | 100% | 5249.05 | 578 / 578 | 100% | 84.43 | 1153 / 1155 |
| breast | 100% | 4102.48 | 459 / 459 | 100% | 72.90 | 1116 / 1118 |
| prostate | 100% | 5568.89 | 245 / 245 | 100% | 101.86 | 501 / 502 |
| stomach | 100% | 5953.69 | 359 / 359 | 100% | 67.69 | 285 / 286 |
| intestine | 100% | 4579.49 | 966 / 966 | 100% | 80.30 | 525 / 527 |
| bladder | 100% | 3859.10 | 21 / 21 | 100% | 91.15 | 502 / 504 |
| thymus | 100% | 5965.36 | 653 / 653 | 100% | 57.61 | 602 / 605 |
| kidney | 100% | 4407.44 | 89 / 89 | 99% | 53.91 | 895 / 901 |
| adrenal gland | 100% | 4437.14 | 258 / 258 | 97% | 45.28 | 224 / 230 |
| brain | 95% | 1874.56 | 2519 / 2642 | 100% | 44.72 | 705 / 705 |
| adipose | 100% | 3599.07 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 47.28 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 64.84 | 29 / 29 |
| spleen | 100% | 6918.44 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 68.95 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 67.76 | 1 / 1 |
| blood vessel | 100% | 3320.16 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 2085.46 | 853 / 861 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1927.05 | 790 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 3060.23 | 900 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006457 | Biological process | protein folding |
| GO_0006487 | Biological process | protein N-linked glycosylation |
| GO_0019082 | Biological process | viral protein processing |
| GO_0009311 | Biological process | oligosaccharide metabolic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0015926 | Molecular function | glucosidase activity |
| GO_0004573 | Molecular function | Glc3Man9GlcNAc2 oligosaccharide glucosidase activity |
| Gene name | MOGS |
| Protein name | Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I) Mannosyl-oligosaccharide glucosidase Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glucosidase I) |
| Synonyms | GCS1 |
| Description | FUNCTION: In the context of N-glycan degradation, cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . FUNCTION: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. . |
| Accessions | ENST00000448666.7 [Q13724-1] A0A3B3ITU6 ENST00000462443.2 B8ZZE2 ENST00000647771.1 A0A8I5KQG9 ENST00000647723.1 ENST00000409065.5 A0A3B3IU81 ENST00000690565.1 A0A3B3IRI7 A0A8I5KTK5 A0A3B3IRI1 ENST00000649075.1 A0A3B3IS52 ENST00000452063.7 [Q13724-2] Q13724 A0A3B3IRK6 C9JDQ1 A0A3B3IRW2 ENST00000650523.1 A0A3B3ITC1 ENST00000414701.1 B4E3B8 ENST00000649854.1 ENST00000647915.1 ENST00000648810.1 ENST00000691308.1 ENST00000647753.1 ENST00000649601.1 |
