ALB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006810Biological processtransport
GO_0098869Biological processcellular oxidant detoxification
GO_0009267Biological processcellular response to starvation
GO_0072732Biological processcellular response to calcium ion starvation
GO_0051902Biological processnegative regulation of mitochondrial depolarization
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0070062Cellular componentextracellular exosome
GO_0032991Cellular componentprotein-containing complex
GO_0005794Cellular componentGolgi apparatus
GO_0072562Cellular componentblood microparticle
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005783Cellular componentendoplasmic reticulum
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0030170Molecular functionpyridoxal phosphate binding
GO_1903981Molecular functionenterobactin binding
GO_0140272Molecular functionexogenous protein binding
GO_0042802Molecular functionidentical protein binding
GO_0019825Molecular functionoxygen binding
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0016209Molecular functionantioxidant activity
GO_0005504Molecular functionfatty acid binding
GO_0015643Molecular functiontoxic substance binding
GO_0005507Molecular functioncopper ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameALB
Protein nameAlbumin
Serum albumin
SynonymshCG_14967
PRO1708
PRO0903
UNQ696/PRO1341
GIG42
PRO2044
PRO2619
PRO2675
GIG20
DescriptionFUNCTION: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc . Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli . Does not prevent iron uptake by the bacterial siderophore aerobactin . .

AccessionsENST00000509063.5
ENST00000295897.9 [P02768-1]
D6RHD5
A0A087WWT3
P02768
B7WNR0
H7C013
Q6LEH2
ENST00000441319.5
ENST00000503124.5
H0YA55
A0A0C4DGB6
ENST00000511370.1
ENST00000476441.6
ENST00000401494.7
D6RCE7
ENST00000415165.6
ENST00000621628.4
C9JKR2