Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 42 studies | 55% ± 23% | |
fibroblast | 37 studies | 47% ± 18% | |
pericyte | 33 studies | 48% ± 23% | |
smooth muscle cell | 29 studies | 51% ± 20% | |
endothelial cell of lymphatic vessel | 23 studies | 59% ± 22% | |
capillary endothelial cell | 15 studies | 56% ± 19% | |
connective tissue cell | 14 studies | 43% ± 17% | |
myofibroblast cell | 14 studies | 44% ± 21% | |
endothelial cell of vascular tree | 14 studies | 49% ± 21% | |
endothelial cell of artery | 13 studies | 62% ± 23% | |
basal cell | 13 studies | 34% ± 19% | |
vein endothelial cell | 12 studies | 60% ± 21% | |
mesothelial cell | 11 studies | 44% ± 20% | |
mast cell | 10 studies | 21% ± 6% | |
type I pneumocyte | 9 studies | 39% ± 16% | |
epithelial cell | 5 studies | 19% ± 4% | |
glomerular endothelial cell | 4 studies | 42% ± 4% | |
type II pneumocyte | 3 studies | 21% ± 4% | |
abnormal cell | 3 studies | 31% ± 13% | |
adventitial cell | 3 studies | 48% ± 10% | |
myoepithelial cell | 3 studies | 68% ± 9% | |
luminal cell of prostate epithelium | 3 studies | 35% ± 0% | |
keratinocyte | 3 studies | 22% ± 4% | |
melanocyte | 3 studies | 27% ± 4% | |
adipocyte | 3 studies | 28% ± 14% | |
hematopoietic stem cell | 3 studies | 27% ± 6% | |
progenitor cell of mammary luminal epithelium | 3 studies | 17% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 36246.40 | 244 / 245 | 99% | 296.63 | 495 / 502 |
thymus | 99% | 22779.62 | 647 / 653 | 98% | 365.04 | 592 / 605 |
breast | 100% | 57016.29 | 459 / 459 | 97% | 264.52 | 1079 / 1118 |
lung | 100% | 38427.43 | 577 / 578 | 94% | 202.33 | 1083 / 1155 |
skin | 100% | 39075.69 | 1805 / 1809 | 93% | 269.63 | 440 / 472 |
uterus | 100% | 58783.74 | 170 / 170 | 92% | 273.32 | 421 / 459 |
esophagus | 98% | 50108.16 | 1412 / 1445 | 91% | 197.53 | 167 / 183 |
ovary | 100% | 29419.61 | 180 / 180 | 77% | 110.31 | 332 / 430 |
bladder | 95% | 48183.33 | 20 / 21 | 80% | 188.09 | 405 / 504 |
adrenal gland | 84% | 10833.54 | 217 / 258 | 82% | 141.07 | 188 / 230 |
intestine | 85% | 38100.61 | 819 / 966 | 79% | 122.09 | 417 / 527 |
kidney | 49% | 7494.16 | 44 / 89 | 93% | 328.35 | 836 / 901 |
stomach | 60% | 19714.59 | 217 / 359 | 80% | 142.77 | 228 / 286 |
pancreas | 3% | 303.54 | 9 / 328 | 98% | 307.47 | 174 / 178 |
adipose | 100% | 67156.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 83962.19 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 290.20 | 80 / 80 |
heart | 99% | 22547.65 | 852 / 861 | 0% | 0 | 0 / 0 |
spleen | 98% | 19167.50 | 237 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 288.07 | 44 / 45 |
muscle | 79% | 10495.99 | 636 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 76% | 71.00 | 22 / 29 |
brain | 8% | 972.12 | 209 / 2642 | 59% | 96.04 | 417 / 705 |
liver | 2% | 241.45 | 4 / 226 | 53% | 67.58 | 216 / 406 |
peripheral blood | 0% | 8.91 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006363 | Biological process | termination of RNA polymerase I transcription |
GO_0006361 | Biological process | transcription initiation at RNA polymerase I promoter |
GO_2000147 | Biological process | positive regulation of cell motility |
GO_0009303 | Biological process | rRNA transcription |
GO_0009306 | Biological process | protein secretion |
GO_0005886 | Cellular component | plasma membrane |
GO_0045121 | Cellular component | membrane raft |
GO_0005739 | Cellular component | mitochondrion |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005901 | Cellular component | caveola |
GO_0005634 | Cellular component | nucleus |
GO_0042802 | Molecular function | identical protein binding |
GO_0042134 | Molecular function | rRNA primary transcript binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CAVIN1 |
Protein name | Caveolae-associated protein 1 (Cavin-1) (Polymerase I and transcript release factor) |
Synonyms | FKSG13 PTRF |
Description | FUNCTION: Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues . Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (By similarity) . The caveolae biogenesis pathway is required for the secretion of proteins such as GASK1A (By similarity). . |
Accessions | ENST00000357037.6 [Q6NZI2-1] Q6NZI2 |