Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 5 studies | 39% ± 15% | |
| glutamatergic neuron | 5 studies | 36% ± 18% | |
| GABAergic neuron | 4 studies | 28% ± 11% | |
| endothelial cell | 3 studies | 26% ± 7% | |
| basal cell | 3 studies | 23% ± 1% | |
| smooth muscle cell | 3 studies | 48% ± 22% | |
| astrocyte | 3 studies | 28% ± 9% | |
| interneuron | 3 studies | 33% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 41% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 4733.78 | 576 / 578 | 82% | 28.72 | 950 / 1155 |
| ovary | 95% | 1313.94 | 171 / 180 | 81% | 17.39 | 347 / 430 |
| skin | 99% | 8912.77 | 1798 / 1809 | 56% | 20.46 | 263 / 472 |
| brain | 92% | 790.51 | 2435 / 2642 | 53% | 7.56 | 372 / 705 |
| esophagus | 42% | 680.38 | 603 / 1445 | 85% | 34.86 | 155 / 183 |
| intestine | 30% | 190.60 | 294 / 966 | 94% | 60.90 | 497 / 527 |
| thymus | 91% | 473.00 | 592 / 653 | 21% | 3.75 | 126 / 605 |
| uterus | 54% | 626.14 | 92 / 170 | 49% | 11.00 | 223 / 459 |
| stomach | 9% | 68.13 | 33 / 359 | 90% | 44.15 | 257 / 286 |
| prostate | 73% | 465.41 | 180 / 245 | 14% | 1.25 | 72 / 502 |
| pancreas | 5% | 16.03 | 17 / 328 | 80% | 28.55 | 143 / 178 |
| breast | 30% | 136.41 | 136 / 459 | 52% | 9.57 | 576 / 1118 |
| bladder | 24% | 111.81 | 5 / 21 | 56% | 22.34 | 284 / 504 |
| blood vessel | 68% | 1007.29 | 910 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 12.92 | 30 / 45 |
| adipose | 44% | 1477.00 | 524 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 4.53 | 9 / 29 |
| spleen | 30% | 124.38 | 73 / 241 | 0% | 0 | 0 / 0 |
| kidney | 19% | 106.20 | 17 / 89 | 6% | 1.58 | 50 / 901 |
| heart | 24% | 192.46 | 204 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 19% | 619.01 | 48 / 258 | 5% | 1.69 | 11 / 230 |
| liver | 4% | 33.19 | 8 / 226 | 14% | 2.35 | 57 / 406 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.17 | 2 / 80 |
| muscle | 2% | 21.65 | 18 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 15.80 | 16 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007605 | Biological process | sensory perception of sound |
| GO_0030214 | Biological process | hyaluronan catabolic process |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
| GO_1900020 | Biological process | positive regulation of protein kinase C activity |
| GO_0051281 | Biological process | positive regulation of release of sequestered calcium ion into cytosol |
| GO_0030213 | Biological process | hyaluronan biosynthetic process |
| GO_0010800 | Biological process | positive regulation of peptidyl-threonine phosphorylation |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045334 | Cellular component | clathrin-coated endocytic vesicle |
| GO_0005905 | Cellular component | clathrin-coated pit |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0030665 | Cellular component | clathrin-coated vesicle membrane |
| GO_0004415 | Molecular function | hyalurononglucosaminidase activity |
| GO_0032050 | Molecular function | clathrin heavy chain binding |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046923 | Molecular function | ER retention sequence binding |
| GO_0005540 | Molecular function | hyaluronic acid binding |
| Gene name | CEMIP |
| Protein name | Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Hyaluronan binding protein involved in hyaluronan depolymerization) Cell migration inducing hyaluronidase 1 |
| Synonyms | KIAA1199 HYBID |
| Description | FUNCTION: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing. . |
| Accessions | Q8WUJ3 ENST00000560027.1 ENST00000495041.1 H0YCE1 H0YL56 ENST00000356249.9 [Q8WUJ3-1] ENST00000394685.8 [Q8WUJ3-1] ENST00000220244.7 [Q8WUJ3-1] |
