Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 20 studies | 25% ± 6% | |
type I pneumocyte | 12 studies | 38% ± 10% | |
type II pneumocyte | 12 studies | 62% ± 19% | |
CD16-positive, CD56-dim natural killer cell, human | 12 studies | 28% ± 6% | |
macrophage | 11 studies | 25% ± 10% | |
non-classical monocyte | 8 studies | 19% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 8 studies | 24% ± 5% | |
classical monocyte | 7 studies | 18% ± 4% | |
retinal rod cell | 7 studies | 28% ± 7% | |
retinal cone cell | 6 studies | 40% ± 16% | |
endothelial cell | 5 studies | 25% ± 10% | |
monocyte | 4 studies | 19% ± 1% | |
neutrophil | 4 studies | 22% ± 4% | |
mature NK T cell | 4 studies | 23% ± 7% | |
club cell | 4 studies | 23% ± 5% | |
epithelial cell | 4 studies | 19% ± 4% | |
CD8-positive, alpha-beta T cell | 3 studies | 20% ± 3% | |
microglial cell | 3 studies | 23% ± 11% | |
abnormal cell | 3 studies | 18% ± 3% | |
myeloid cell | 3 studies | 23% ± 1% | |
gamma-delta T cell | 3 studies | 17% ± 1% | |
glutamatergic neuron | 3 studies | 32% ± 12% | |
neuron | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 3262.86 | 459 / 459 | 98% | 59.47 | 1093 / 1118 |
brain | 99% | 3392.86 | 2603 / 2642 | 99% | 74.25 | 695 / 705 |
lung | 100% | 22974.13 | 578 / 578 | 97% | 232.06 | 1119 / 1155 |
prostate | 100% | 3659.36 | 244 / 245 | 96% | 35.82 | 483 / 502 |
bladder | 100% | 4201.86 | 21 / 21 | 95% | 77.51 | 478 / 504 |
skin | 96% | 2465.84 | 1742 / 1809 | 98% | 59.28 | 463 / 472 |
thymus | 100% | 3102.10 | 652 / 653 | 89% | 25.08 | 538 / 605 |
adrenal gland | 100% | 3546.06 | 258 / 258 | 88% | 38.43 | 203 / 230 |
ovary | 100% | 3228.98 | 180 / 180 | 88% | 34.62 | 377 / 430 |
kidney | 100% | 2949.17 | 89 / 89 | 87% | 97.14 | 787 / 901 |
uterus | 100% | 4200.69 | 170 / 170 | 87% | 54.64 | 400 / 459 |
intestine | 100% | 3305.22 | 963 / 966 | 87% | 34.42 | 456 / 527 |
esophagus | 96% | 3108.25 | 1384 / 1445 | 86% | 39.61 | 158 / 183 |
stomach | 91% | 2129.49 | 328 / 359 | 84% | 34.14 | 241 / 286 |
pancreas | 74% | 1095.92 | 243 / 328 | 92% | 34.56 | 164 / 178 |
liver | 64% | 1022.18 | 144 / 226 | 44% | 18.91 | 177 / 406 |
adipose | 100% | 4012.99 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 91.03 | 29 / 29 |
peripheral blood | 100% | 13208.74 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 19983.61 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 91.65 | 1 / 1 |
blood vessel | 100% | 3858.45 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1885.92 | 823 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 41.82 | 76 / 80 |
tonsil | 0% | 0 | 0 / 0 | 71% | 24.50 | 32 / 45 |
muscle | 18% | 185.02 | 144 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0036148 | Biological process | phosphatidylglycerol acyl-chain remodeling |
GO_0036151 | Biological process | phosphatidylcholine acyl-chain remodeling |
GO_0006656 | Biological process | phosphatidylcholine biosynthetic process |
GO_0060041 | Biological process | retina development in camera-type eye |
GO_0045732 | Biological process | positive regulation of protein catabolic process |
GO_0008654 | Biological process | phospholipid biosynthetic process |
GO_0043129 | Biological process | surfactant homeostasis |
GO_0030163 | Biological process | protein catabolic process |
GO_2001246 | Biological process | negative regulation of phosphatidylcholine biosynthetic process |
GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0005811 | Cellular component | lipid droplet |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0035577 | Cellular component | azurophil granule membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0047192 | Molecular function | 1-alkylglycerophosphocholine O-acetyltransferase activity |
GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0042171 | Molecular function | lysophosphatidic acid acyltransferase activity |
GO_0047191 | Molecular function | 1-alkylglycerophosphocholine O-acyltransferase activity |
GO_0047159 | Molecular function | plasmalogen synthase activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0047184 | Molecular function | 1-acylglycerophosphocholine O-acyltransferase activity |
Gene name | LPCAT1 |
Protein name | Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3) |
Synonyms | PFAAP3 AYTL2 |
Description | FUNCTION: Exhibits acyltransferase activity . Exhibits acetyltransferase activity (By similarity). Activity is calcium-independent (By similarity). Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) . Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity). Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (By similarity). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (By similarity). Involved in the regulation of lipid droplet number and size . . |
Accessions | Q8NF37 A0A0G2JRI7 ENST00000626646.1 ENST00000611696.3 ENST00000283415.4 ENST00000625809.2 A0A0G2JQ62 ENST00000475622.5 |